Can a headband help your brain take out the trash after a bad Night's sleep?
NCT ID NCT07608614
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how sleep helps clean the brain. Researchers will use special MRI scans to see the brain's waste-clearing system in 16 healthy young adults. They will also test a headband that tracks brain waves and uses mild electrical pulses to improve sleep and brain function after a short night's sleep. The goal is to understand how poor sleep affects memory and whether the headband can help.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 16 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Physically and psychologically healthy 2. Good habitual sleep between 6 and 10 hours in duration, as assessed by questionnaire and pre-study week sleep/wake diary 3. Regular bedtimes, habitually getting up between 05:00 and 09:00, as assessed by questionnaire and pre-study week sleep/wake diary Exclusion Criteria: * Subjects who have any type of non-MRI compatible bioimplant activated by mechanical, electronic, or magnetic means (e.g., cochlear implants, pacemakers, neurostimulators, biostimulators, electronic infusion pumps, etc.), because such devices may be displaced or malfunction. * Subjects who have any type of ferromagnetic bioimplant that could potentially be displaced. * Subjects who have cerebral aneurysm * Subjects who may have shrapnel imbedded in their bodies (such as from war wounds), metal workers and machinists (potential for metallic fragments in or near the eyes). * Minors (younger than 18 years) * Pregnant women ( Participants of childbearing potential will receive a urine pregnancy test. If the test is positive, the participant will be excluded) * Breastfeeding * Subjects who cannot adhere to the experimental protocols for any reason, or have an inability to communicate with the researcher. * no clinical disorders and/or illnesses, no psychiatric illnesses), as assessed by history and questionnaires * no alcohol during study and no normal excessive alcohol consumption assessed by questionnaire * No history of drug or alcohol abuse in the past year and no history of methamphetamine abuse, as assessed by questionnaires. * Not a dependent smoker or vaper, and not morning dependent on tobacco, nicotine, or cannabis, as assessed by questionnaire. * No history of moderate to severe brain injury, as assessed by questionnaire * No anti-psychotic medication for ADHD/ADD, as assessed by questionnaire * No previous adverse reaction to sleep deprivation, as assessed by questionnaire * Not vision-impaired unless corrected back to normal. * Not hearing impaired unless corrected to normal, as assessed by questionnaire * Not pregnant, as assessed by history and questionnaire * No sleep or circadian disorder, as assessed by questionnaires * No use of melatonin within 1 week of study enrollment * No travel across more than one time zone within one month of entering the study and no crossing times zones during study participation, as assessed by questionnaire. * No shift work within three months of entering the study and no shift work during duration study participation, as assessed by questionnaire. * epilepsy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Washington School of Medicine
RECRUITINGSeattle, Washington, 98125, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can fixing abnormal brain vessels help the brain clear its waste?
- Does soreness after exercise disrupt sleep more for people with insomnia?
- Can teaching parents about sleep help kids with developmental conditions?
- Can a bed that changes temperature deepen your sleep?
- Can zapping the ear during a nap boost memory?