Can a daily pill give you better skin? new study tests two supplements against placebo

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Skin type origin: Asian in China * Age: from 40 to 65 years old * Gender: female * Specific criteria: • All skin type on the face Dry, dry combination, normal 1. presenting with a lack of elasticity to the face, inclusion grade ≤ 6 according 10 points scale 2. presenting with a lack of density to the face, inclusion grade ≤ 6 according 10 points scale 3. presenting with wrinkles on crow's feet area, grade ≥ 2 according to Skin ageing atlas Vol.2 (p.41) 4. presenting with pigmentary spots with at least one with diameter ≥ 3mm * Usual or occasional user of food supplements * Able to give her informed consent Exclusion Criteria: The non-inclusion general criteria were the following ones: * allergies or reactivity to cosmetic products, * for the subjects undergoing hormonal treatment; change of treatment within 3 months preceding the inclusion visit, * expectation of change in the current hormonal treatment during the study, * anti-allergic, antibiotic, anti-inflammatory, dermatological treatment or corticosteroid therapy within 2 weeks before the inclusion visit, * having a chronic pathology, * performing or prevision to perform another test during the study or during the exclusion period, * employee of the COSderma laboratory, * pregnant or breast-feeding woman, * woman not taking precaution to prevent pregnancy. The non-inclusion specific criteria were the following ones: * application of care products to the face within 48 hours preceding the inclusion visit, * application of make-up products to the face the day of the inclusion visit, * face wash with any other means than clear water (no soap or cleanser) on the day of the inclusion visit, * application of self-tanning products to the face within 4 weeks preceding the inclusion visit, * Oral intake of food supplement within 1 month preceding the inclusion visit, * cutaneous marks on the face which could interfere with the skin's clinical signs assessment (pigmentation issues, scar tissues, over-developed hairiness, too many ephelides and naevi, sunburns...), * solar exposition (natural sun or UVA or heliotherapy treatment) within 4 weeks preceding the inclusion visit and expectation of solar exposition (natural or UVA) during the study, * Vitamin A acid treatment or its derivatives within 3 months preceding the pre-inclusion visit, * Retinoid based oral treatment within 6 months before the pre-inclusion visit, or local treatment within 2 months prior to this visit, * Carotene based treatment within 4 weeks preceding the inclusion visit, * expectation or having undergone aesthetic or dermatological surgery on the face.