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New drug combo aims to slow advanced lung cancer in patients with EGFR mutations

NCT ID NCT06670196

First seen Jan 05, 2026 · Last updated Jun 18, 2026 · Updated 20 times

Summary

This study tests whether adding the experimental drug SKB264 to the standard targeted therapy osimertinib helps people with advanced EGFR-mutant non-small cell lung cancer live longer without their cancer growing. About 420 adults who have not had prior treatment for advanced disease will be randomly assigned to receive either the combination or osimertinib alone. The main goal is to see if the combination delays cancer progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sun Yat-Sen University Cancer Center

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510060, China

  • Sun Yat-Sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.