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Stand up or walk? study tests best way to break up sitting time

NCT ID NCT05316571

Knowledge-focused Sponsor: University of North Carolina, Chapel Hill Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how interrupting long periods of sitting with short walking or standing breaks affects heart and blood vessel health. Researchers will compare different break schedules in 56 sedentary adults aged 30-60. The goal is to find simple, practical strategies that could eventually lead to public health advice on reducing heart disease risk.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
walking and standing breaks
What this could lead to
If successful, this study could provide clear, simple guidelines on how often to interrupt sitting to improve heart health.
What could go wrong
This is a small, early-stage study with only 56 participants, so results may not apply to everyone. It tests short-term effects, not long-term disease prevention.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 56 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2022

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged between 30-60 years * Insufficiently active: self-reported exercise \<90 minutes per week for the past 3 months * Sedentary: self-reported sitting \>8 hours per day * Self-reported ability to walk 4 blocks and climb 2 flights of stairs * Possession of cellular phone able to receive text messages Exclusion Criteria: * Use of assisted-walking devices * Comorbid condition that would limit the ability to reduce sedentary behavior (e.g., musculoskeletal condition, current chemotherapy) * Plans for major surgery within next 3 months * Recent history (\<1 year) of ischemic heart disease, chronic heart failure, stroke, or chronic kidney disease * Recent (\< 1 year) or planned bariatric surgery * Systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥100 mmHg * Current or recent (within last 6 months) pregnancy; current or recent (within last 3 months) breastfeeding * Morbidly obesity (BMI \>40 kg/m\^2) or underweight (BMI \<18.5 kg/m\^2) * Use of anti-hypertensive drugs * Use of glucose-controlling medication * Heavy alcohol consumption (\>15 drinks per week)

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Conditions

The condition(s) this trial relates to.

Sedentary Behavior

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sedentary behavior Sedentary time

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • University of North Carolina at Chapel Hill

    RECRUITING

    Chapel Hill, North Carolina, 27599, United States

    Contact Email: •••••@•••••

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