Stitch showdown: which cesarean closure method lowers niche risk?
NCT ID NCT07554001
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 366 women having their first planned cesarean section to see if closing the uterine incision with one layer of stitches or two layers affects the chance of developing a uterine niche (a small pocket in the scar). Participants were asked about symptoms like spotting or pain. The goal is to find out which method might be safer.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If one method clearly reduces niche risk, it could guide surgeons to choose the better closure technique for future cesarean sections.
- What could go wrong
- This is a completed observational comparison, not a large randomized trial, so results may not apply to all women or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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366 people
The number who actually took part.
- Started
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Feb 2024
- Finished
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Feb 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years. * Women who undergo first elective cesarean section (CS). Exclusion Criteria: * Women with a previous CS * Inadequate possibility for counselling (e.g. indication for CS without being informed about the study previously, women in severe pain without adequate therapy * previous major uterine surgery (e.g. laparoscopic or laparotomy fibroid resection, septum resection), Women with known causes of menstrual disorders (e.g. cervical dysplasia, communicating hydro salpinx, uterine anomaly * Placenta increta or percreta during the current pregnancy * ≥ Three foetuses during the current pregnancy. * Placenta previa * Twins
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kafrelsheikh University
Kafr ash Shaykh, Kafrelsheikh, 33516, Egypt