Could a silver gel halt cavities without the drill?
NCT ID NCT05395065
First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time
Summary
This study is testing whether applying a silver diamine fluoride gel followed by a fluoride varnish can stop cavities in children's baby teeth. Researchers will follow 237 children for a year to see how many cavities become inactive and whether parents are satisfied with the treatment. The goal is to find a simple, non-invasive way to manage tooth decay in young children.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Silver diamine fluoride gel and sodium fluoride varnish
- What this could lead to
- If effective, this could offer a simple, non-invasive way to stop cavities in children's baby teeth, potentially reducing the need for drilling or fillings.
- What could go wrong
- This is an observational study without a comparison group, so results may be less conclusive. The gel may cause tooth staining, and long-term effectiveness is still uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
237 people
The number who actually took part.
- Started
-
Jul 2022
- Finished
-
Jan 2024
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The children will be recruited from five schools (Centro Educativo Inicial) in Puno, Peru
- Ages
-
3 to 4 years
- Sex
-
Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * At least one active caries lesion Good general health by parent report Exclusion Criteria: * Unable to cooperate with exam or procedure
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Dental caries in children are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UGEL Manazo
Puno, Puno, Peru
-
UGEL Puno 210001 Las Torres
Puno, Puno, Peru
-
UGEL Puno Magisterial
Puno, Puno, Peru
-
UGEL San Jose
Puno, Puno, Peru
-
UGEL Villa del Lago
Puno, Puno, Peru
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Bottled water with fluoride put to the test against childhood cavities
- Can a new tooth filling make Kids' cavity repairs last longer?
- Cavity fighters under the microscope: new study tests fluoride and chlorhexidine on Kids' saliva
- New study tests easier tooth filling for Kids' cavities
- Dental showdown: which crown technique saves Kids' teeth best?
- Which glue holds Kids' crowns best? new study aims to find out