New tetanus shot under study in 10,000 people
NCT ID NCT07107932
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This large real-world study is testing an injection called siltartoxatug (Sintetol®) to prevent tetanus in people who have been injured. Researchers will follow 10,000 participants for 90 days to see if the shot prevents tetanus and to track any side effects. The goal is to learn how well this treatment works in everyday medical settings.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- siltartoxatug injection (Sintetol®)
- What this could lead to
- If successful, this could confirm siltartoxatug as a safe and effective way to prevent tetanus after an injury, potentially replacing current treatments.
- What could go wrong
- This is an observational registry, not a controlled trial, so results may be less definitive. Side effects are possible, and the study does not compare siltartoxatug to other treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients receiving Siltartoxatug for tetanus prophylaxis following injury and providing informed consent for participation.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1.Having received or will receive Siltartoxatug for tetanus prophylaxis following injury; * 2\. Provided signed informed consent by themselves or their legal representatives. Exclusion Criteria: * None
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Shaoxing Central Hospital
RECRUITINGShaoxing, Zhejiang, 312030, China
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The Second Affiliated Hospital of Shantou University
NOT_YET_RECRUITINGShantou, Guangdong, 515041, China
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Xiangyun County People's Hospital
NOT_YET_RECRUITINGXiangyun, Yunnan, 672100, China
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Zhoushan Putuo District People's Hospital
NOT_YET_RECRUITINGZhoushan, Zhejiang, 316100, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Tetanus immunity under the microscope: do antibodies hold up after 2.5 years?
- One shot, six protections: could a single vaccine replace multiple infant shots?
- Can one shot replace six? a new vaccine aims to protect infants from six diseases at once
- Can a Lab-Made antibody outperform standard tetanus shots?
- One shot, six protections: can a new vaccine match current standards?
- Can a new vaccine shield older kids and adults from three deadly infections?