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Silk bandage could ease recovery for transgender chest surgery

NCT ID NCT06921148

First seen Jun 12, 2026 · Last updated Jun 22, 2026 · Updated 2 times

Summary

This study tests a silk-based wound dressing against a standard adhesive dressing in 50 adults undergoing double-incision mastectomy for female-to-male gender affirmation. Each patient serves as their own control, with one side of the chest getting the silk dressing and the other getting standard care. The goal is to see if the silk dressing reduces skin injuries, infections, and premature dressing removal, and improves scar healing from the patient's and surgeon's perspectives.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University Health

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sylk Wound Dressing (silk bioprotein device)

What this could lead to

If it works, this could offer a better, gentler wound dressing option for people undergoing gender-affirming mastectomy, reducing skin irritation and improving healing.

What could go wrong

This is a small, early-stage study with only 50 participants. The silk dressing may not prove significantly better than standard care, and individual results may vary.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.