Liquid vs tablet: which sildenafil form do men prefer?
NCT ID NCT07676617
First seen Jun 30, 2026 · Last updated Jul 02, 2026 · Updated 2 times
Summary
This study looks at whether men with mild-to-moderate erectile dysfunction are more satisfied with sildenafil in a liquid suspension form compared to tablets that dissolve in the mouth. Researchers will review records of men who took each form for three months. The goal is to see if the liquid version improves satisfaction, effectiveness, or side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- sildenafil
- What this could lead to
- If the suspension is preferred, it could offer a more convenient or palatable option for men with erectile dysfunction.
- What could go wrong
- This is a small, retrospective study with only 55 participants, so results may not apply to everyone. Side effects like headache or flushing are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
55 people
The number who actually took part.
- Started
-
Jun 2026
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Data from patients with ED attending the Andrology Outpatient Clinic of the Urology Department of the IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation will be retrospectively analyzed.
- Ages
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18 to 75 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-75 * Male * Sexually active (at least 2 sexual encounters per week) * IIEF-EF between 11 and 25 at baseline Exclusion Criteria: * hypogonadism (total testosterone \< 3.5 ng/mL) * previous pelvic surgery * ED on a neurogenic basis * concomitant use of other ED therapies * conical therapy with nitrates or other contraindicated drugs in combination with sildenafil * hypersensitivity to the active ingredient * patients for whom sexual activity is not recommended (e.g. patients with serious cardiovascular disorders, such as unstable angina or severe heart failure). * patients who have lost vision in one eye due to non-arteritic anterior ischemic optic neuropathy (NAION), whether or not this event was related to previous use of a phosphodiesterase type 5 (PDE5) inhibitor * patients with severe hepatic impairment, hypotension (blood pressure \<90/50 mmHg), recent history of stroke or myocardial infarction and known hereditary degenerative retinal diseases, such as retinitis pigmentosa * patients treated with guanylate cyclase stimulants, such as riociguat.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, 20122, Italy
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