New Dual-Action antibody tested in advanced cancers
NCT ID NCT04606472
First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 32 times
Summary
This early-phase study tests a new drug called SI-B003 in 60 people with advanced solid tumors that have not responded to standard treatments. The drug is a bispecific antibody designed to target two immune checkpoints (PD-1 and CTLA-4) to help the immune system fight cancer. The main goals are to find a safe dose and check for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Beijing Cancer Hospital
Beijing, Beijing Municipality, 100142, China
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Chongqing University Cancer Hospital
Chongqing, Chongqing Municipality, China
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Henan Cancer Hospital
Zhengzhou, Henan, 450008, China
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Hubei Cancer Hospital
Wuhan, Hubei, China
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Shanghai Central Hospital
Shanghai, Shanghai Municipality, China
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The First Affiliated Hospital of Xiamen University
Xiamen, Fujian, China
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Union Hospital Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
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West China Hospital, Sichuan University
Chengdu, Sichuan, China
Conditions
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