Can stump pressure guide shunt use in carotid surgery?
NCT ID NCT00967486
First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time
Summary
Researchers compare two ways of managing blood flow during carotid endarterectomy, a surgery that clears plaque from the neck artery to prevent stroke. One group receives a shunt routinely, while the other gets a shunt only when a pressure measurement suggests it is needed. The trial tracks complications such as mini-strokes, bleeding, heart attack, and blood clots in the operated artery to see which approach is safer.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- carotid endarterectomy with selective shunting based on stump pressure
- What this could lead to
- If selective shunting works, surgeons could avoid unnecessary shunts in some patients, reducing procedure time and shunt-related risks while keeping stroke protection.
- What could go wrong
- This is a single-center study with 200 patients, so results may not apply broadly. Shunting decisions based on stump pressure might miss patients who need a shunt, and the trial may not show a clear difference between the two approaches.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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200 people
The number who actually took part.
- Start date
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Dec 2006
- Finished
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Jun 2009
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with a SP \>= 50 mmHg will be randomized to receive a shunt or not receive a shunt. Exclusion Criteria: * Patients that will be excluded are those who present for a redo CEA, have had a coronary artery bypass graft (CABG), permanent stroke, and or a contralateral artery total occlusion of \> 30%. * Finally, consented patients with a stump pressure of \<= 50 mm Hg will be excluded from the study and receive standard of care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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(Vascular Center of Excellence)
Charleston, West Virginia, 25304, United States