Could a 3-Week radiation course beat the standard 5-Week for cervical cancer?
NCT ID NCT07625943
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a shorter, 3-week course of radiation works as well as the standard 5-week course for women with locally advanced cervical cancer. About 396 women will be randomly assigned to one of the two schedules, both combined with chemotherapy. If the shorter schedule is equally effective, it could make treatment more convenient and help more women complete therapy, especially in busy cancer centers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 396 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Jan 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Female participants aged 18 to 65 years. Histopathologically confirmed cervical cancer. FIGO stage IB3 to IIIC1. Suitable for definitive concurrent chemoradiation. ECOG performance status 0 to 2. Adequate hematological, renal, and hepatic function. Able and willing to provide informed consent. Exclusion Criteria: ECOG performance status 3 or higher. FIGO stage IIIC2, IVA, or IVB. Prior pelvic radiotherapy or prior chemotherapy for cervical cancer. Inflammatory bowel disease. Hydronephrosis. Pregnancy. Synchronous malignancy. Any serious medical condition that would interfere with protocol treatment or follow-up.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Cancer Institute, All India Institute of Medical Sciences, New Delhi, India
RECRUITINGNew Delhi, New Delhi, 110029, India
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Other studies related to the condition(s) this trial covers.
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