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New shock treatment aims to prevent dangerous heart rhythms in ICU

NCT ID NCT02118467

First seen Jan 17, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This study tests whether two drugs, phenylephrine and vasopressin, can lower the risk of dangerous heart rhythm problems in ICU patients with shock compared to standard drugs norepinephrine and epinephrine. About 836 adults with shock not improving after fluids will be randomly assigned to one of the two drug pairs. The main goal is to see if the newer drug combination reduces hospital deaths and heart rhythm issues.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Chicago Medical Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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