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New pill targets HER2 lung cancer in major trial

NCT ID NCT06452277

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 11, 2026 · Updated 7 times

Summary

This Phase 3 trial is testing a new oral drug, sevabertinib, against standard intravenous chemotherapy for people with advanced non-small cell lung cancer that has specific HER2 mutations. About 444 participants will be randomly assigned to receive either sevabertinib twice daily or standard treatment. The study aims to see if sevabertinib can delay cancer growth and improve survival. Those on standard treatment whose cancer worsens may switch to sevabertinib.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Sevabertinib (tablet taken by mouth)
What this could lead to
If it works, this could offer a new first-line targeted treatment option for people with advanced HER2-mutated lung cancer, potentially improving how long they live without their cancer growing.
What could go wrong
This is an early Phase 3 trial, so results are not yet known. The drug may not work better than current treatments, and side effects could be severe. Only people with a specific HER2 mutation can benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 444 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2024

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant must be ≥18 years of age or over the legal age of consent in countries where that is greater than 18 years at the time of signing the informed consent. * Documented histologically or cytologically confirmed locally advanced non-squamous NSCLC, not suitable for definitive therapy or metastatic non-squamous NSCLC at screening (small cell or mixed histologies are excluded) (Stage III-IV NSCLC). * Documented activating HER2 mutation in the tyrosine kinase domain (TKD) assessed by tissue molecular test in a CLIA-certified (US sites) or an equally accredited (outside of the US) local laboratory. However, participants may be included at the discretion of the investigator if the laboratory performing the assay is not CLIA or similar certified but the laboratory is locally accredited. * No prior systemic therapy for locally advanced or metastatic disease. No prior treatment with a HER2 ex20ins-targeted therapy (e.g. poziotinib, trastuzumab deruxtecan). Participants who received adjuvant or neoadjuvant therapy are eligible if the adjuvant/neoadjuvant therapy was completed at least 12 months prior to the start of screening. * Eligible to receive treatment with the selected platinum-based doublet-chemotherapy (i.e. cisplatin/pemetrexed or carboplatin/pemetrexed) and pembrolizumab in accordance with the SmPC/Product Information. Exclusion Criteria: * Known history of prior malignancy except if the participant has undergone potentially curative therapy with no evidence of that disease recurrence for five years since initiation of that therapy. Exception: the following cancer types are acceptable within five years if curatively treated or under surveillance: * a. in situ cancers of cervix, breast, or skin, * b. superficial bladder cancer (Ta, Tis and T1), * c. limited-stage prostate cancer, * d. basal or squamous cancers of the skin. * Tumors with targetable alterations with approved available therapy, with the exception of HER2 mutation in the TKD. * Inability to discontinue treatment with chronic systemic corticosteroids. Participants who require intermittent use of bronchodilators, inhaled steroids, or local steroid injections would not be excluded from the study. Replacement therapy (e.g., physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency) is acceptable, provided that the dose is stable for \>4 weeks prior to planned start of study intervention. * Pre-existing peripheral neuropathy that is Grade ≥2 by CTCAE (v5.0). * History of severe hypersensitivity reaction to treatment with a monoclonal antibody. * Prior radiotherapy outside of the brain within 21 days before of planned start of study intervention. Participants must have recovered from all radiation-related toxicities and not require corticosteroids.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    98 sites in 20 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • A Beneficencia Portuguesa de Sao Paulo - Hospital BP Mirante

    RECRUITING

    São Paulo, 01323-030, Brazil

  • AORN San Giuseppe Moscati Avellino - U.O.C. Oncologia Medica

    COMPLETED

    Avellino, 83100, Italy

  • APHP - Hopital Cochin - Service de Pneumologie

    WITHDRAWN

    Paris, Île-de-France Region, 75014, France

  • ASST Sette Laghi_Ospedale Macchi - Oncologia

    WITHDRAWN

    Varese, 21100, Italy

  • AZ Delta | Clinical Trial Center - Pneumology

    ACTIVE_NOT_RECRUITING

    Roeselare, West Flanders, 8800, Belgium

  • Aalborg University hospital - oncology department

    COMPLETED

    Aalborg, North Denmark Region / Region Nordjylland, 9000, Denmark

  • Aarhus Universitetshospital

    COMPLETED

    Aarhus N, Central Denmark Region / Region Midtjylland, 8200, Denmark

  • Adana Sehir Egitim ve Arastirma Hastanesi

    COMPLETED

    Yüreğir, 1370, Turkey (Türkiye)

  • AdventHealth Cancer Institute Orlando

    NOT_YET_RECRUITING

    Orlando, Florida, 32804, United States

  • Allegheny General Hospital

    RECRUITING

    Pittsburgh, Pennsylvania, 15212, United States

  • Ankara Bilkent Sehir Hastanesi

    ACTIVE_NOT_RECRUITING

    Bilkent Çankaya, Ankara, 6800, Turkey (Türkiye)

  • Ankara Etlik Sehir Hastanesi

    NOT_YET_RECRUITING

    Yenimahalle, 6170, Turkey (Türkiye)

  • Antwerp University Hospital | Oncology Department

    WITHDRAWN

    Antwerp, Antwerp, 2650, Belgium

  • Assuta Ashdod Public Hospital (R.A)

    ACTIVE_NOT_RECRUITING

    Ashdod, 7747629, Israel

  • Austin Hospital - Olivia Newton John Cancer Research Institute

    ACTIVE_NOT_RECRUITING

    Heidelberg, Victoria, 3084, Australia

  • Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello - Oncologia Medica

    ACTIVE_NOT_RECRUITING

    Palermo, 90146, Italy

  • Azienda Ospedaliero-Universitaria Di Bologna IRCCS_Policlinico Sant'Orsola - UOC Oncologia Medica

    ACTIVE_NOT_RECRUITING

    Bologna, 40138, Italy

  • Azienda Ospedaliero-Universitaria San Luigi Gonzaga - Oncologia Medica

    ACTIVE_NOT_RECRUITING

    Orbassano, 10043, Italy

  • BC Cancer | Vancouver

    COMPLETED

    Vancouver, British Columbia, V5Z 4E6, Canada

  • Beacon Hospital

    NOT_YET_RECRUITING

    Petaling Jaya, Selangor, 46050, Malaysia

  • Beijing Cancer Hospital - Oncology Department

    ACTIVE_NOT_RECRUITING

    Beijing, Beijing Municipality, 100142, China

  • Beijing Hospital

    ACTIVE_NOT_RECRUITING

    Beijing, Beijing Municipality, 100730, China

  • Beijing chest hospital, Capital Medical University

    ACTIVE_NOT_RECRUITING

    Beijing, Beijing Municipality, 101149, China

  • Belfast City Hospital | Oncology

    WITHDRAWN

    Belfast, Northern Ireland, BT12 7AB, United Kingdom

  • Brampton Civic Hospital | Oncology

    RECRUITING

    Brampton, Ontario, L6R 3J7, Canada

  • Budapesti Uzsoki Utcai Korhaz - Tüdőgyógyászati Osztály

    WITHDRAWN

    Budapest, 1145, Hungary

  • CHU Montpellier - Hopital Arnaud de Villeneuve - Service oncologie thoracique

    ACTIVE_NOT_RECRUITING

    Montpellier, Occitanie, 34091, France

  • CHU de Rouen - Hopital Charles Nicolle - Service de Pneumologie

    WITHDRAWN

    Rouen, Normandy, 76031, France

  • CHULN - Hospital Pulido Valente

    RECRUITING

    Lisbon, 1769-001, Portugal

  • Calvary Mater Hospital Newcastle - Oncology

    ACTIVE_NOT_RECRUITING

    Waratah, New South Wales, 2298, Australia

  • Cancer Hospital, Chinese Academy of Medical Sciences

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100000, China

  • CardioMed S.R.L.

    NOT_YET_RECRUITING

    Cluj-Napoca, 400015, Romania

  • Careggi University Hospital - Oncologia Clinica

    ACTIVE_NOT_RECRUITING

    Florence, 50134, Italy

  • Centre Antoine Lacassagne - Departement Oncologie

    ACTIVE_NOT_RECRUITING

    Nice, Provence-Alpes-Côte d'Azur Region, 06100, France

  • Centre Hospitalier Intercommunal Creteil - Service de pneumologie

    ACTIVE_NOT_RECRUITING

    Créteil, Île-de-France Region, 94010, France

  • Centre Hospitalier Michallon Grenoble - Service pneumologie

    ACTIVE_NOT_RECRUITING

    La Tronche, Auvergne-Rhône-Alpes, 38700, France

  • Centre Hospitalier Universitaire de Limoges - unite oncologie thoracique

    ACTIVE_NOT_RECRUITING

    Limoges, New Aquitaine, 87000, France

  • Centro Médico Privado CEMAIC

    WITHDRAWN

    Córdoba, X5008HHW, Argentina

  • Centro Paulista de Oncologia (CPO) - Sao Paulo - Faria Lima

    RECRUITING

    Brasília, Federal District, 04538-132, Brazil

  • Centro Ricerche Cliniche Di Verona S.r.l. - Oncologia

    WITHDRAWN

    Verona, 37134, Italy

  • Centro de Educacion Medica e Investigaciones Clinicas "Norberto Quirno" (CEMIC)

    WITHDRAWN

    Buenos Aires, C1431FWO, Argentina

  • Centro de Investigaciones Clínicas, Clínica Viedma

    WITHDRAWN

    Viedma, Río Negro Province, R8500ACE, Argentina

  • Centro de Pesquisa da Clínica de Oncologia Reichow

    RECRUITING

    Blumenau, Santa Catarina, 89010-340, Brazil

  • Centro di Riferimento Oncologico di Aviano - Oncologia Medica e dei Tumori Immuno-Correlati

    ACTIVE_NOT_RECRUITING

    Aviano, 33081, Italy

  • Centrul de Oncologie Sfantul Nectarie

    ACTIVE_NOT_RECRUITING

    Craiova, 200745, Romania

  • Charité Universitätsmedizin Berlin CBF - Med. Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie

    NOT_YET_RECRUITING

    Berlin, 12203, Germany

  • Chi-Mei Medical Center, Liouyine

    COMPLETED

    Tainan, 73657, Taiwan

  • Chonnam National University Hwasun Hospital | Pulmonology and Critical Care Medicine

    NOT_YET_RECRUITING

    Hwasun-gun, Jeollanam-do, 58128, South Korea

  • Chung Shan Medical University Hospital

    RECRUITING

    Taichung, 402306, Taiwan

  • Chungbuk National University Hospital | Hematology and Oncology

    NOT_YET_RECRUITING

    Chungcheongbuk-do, North Chungcheong, 28644, South Korea

  • Clinica Integral Internacional de Oncologia S. de R.L. de C.V.

    NOT_YET_RECRUITING

    Puebla City, 72530, Mexico

  • Columbia Asia Hospital Bukit Rimau

    NOT_YET_RECRUITING

    Shah Alam, Selangor, 40460, Malaysia

  • Complex Oncology Center - Plovdiv EOOD

    NOT_YET_RECRUITING

    Plovdiv, Plovdiv Province, 4004, Bulgaria

  • Complexo Hospitalario Universitario A Coruna | Oncologia

    WITHDRAWN

    A Coruña, 15006, Spain

  • Concord Repatriation General Hospital - Medical Oncology Clinical Trials Unit

    COMPLETED

    Concord, New South Wales, 2139, Australia

  • Curie Oncology | Farrer

    COMPLETED

    Singapore, 329563, Singapore

  • Docrates Mehiläinen Syöpäsairaala

    WITHDRAWN

    Helsinki, Uusimaa, 00180, Finland

  • Dolnoslaskie Centrum Onkologii, Pulmonologii i Hematologii

    WITHDRAWN

    Wroclaw, 53-413, Poland

  • Ege Universitesi Tip Fakultesi Hastanesi

    ACTIVE_NOT_RECRUITING

    Izmir, 35100, Turkey (Türkiye)

  • Fakultna nemocnica Trnava

    ACTIVE_NOT_RECRUITING

    Trnava, 917 75, Slovakia

  • Fakultní Nemocnice Olomouc - Klinika plicních nemocí a tuberkulózy

    WITHDRAWN

    Olomouc, Olomouc Region, 779 00, Czechia

  • Fondazione IRCCS Istituto Nazionale dei Tumori - S. C. Oncologia Medica 1

    ACTIVE_NOT_RECRUITING

    Milan, 20133, Italy

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOSD Oncologia Toraco-Polmonare

    ACTIVE_NOT_RECRUITING

    Roma, 00168, Italy

  • Fujian Cancer Hospital

    ACTIVE_NOT_RECRUITING

    Fuzhou, Fujian, 350014, China

  • Fundacao Champalimaud | Centro Clinico Champalimaud - Unidade Investigacao Clinica

    RECRUITING

    Lisbon, 1400-038, Portugal

  • Fundacao Pio XII - Hospital de Cancer de Barretos

    RECRUITING

    Jaú, São Paulo, 14784-400, Brazil

  • Fundacion Instituto Valenciano De Oncologia | Oncologia

    WITHDRAWN

    Valencia, 46009, Spain

  • Fundación Cenit para la Investigación en Neurociencias

    WITHDRAWN

    Buenos Aires, C1125 ABD, Argentina

  • General Hospital of Athens "Alexandra''-Plasma Cell Dyscrasias,Department of Clinical Therapeutics,School of Medicine,NKUA

    ACTIVE_NOT_RECRUITING

    Athens, 11528, Greece

  • General University Hospital Of Larissa-Department of Medical Oncology

    WITHDRAWN

    Larissa, 41110, Greece

  • Genesis Hospital- Department of Pathological Oncology

    WITHDRAWN

    Pylaia Thessaloniki, 555 35, Greece

  • Geniko Nosokomeio Thessalonikis George Papanikolaou-Pulmonary Department

    ACTIVE_NOT_RECRUITING

    Thessaloniki, 57010, Greece

  • Gleneagles Penang Medical Center

    NOT_YET_RECRUITING

    George Town, Pulau Pinang, 10050, Malaysia

  • Guangxi Medical University (GXMU) - Affiliated Tumor Hospital

    ACTIVE_NOT_RECRUITING

    Nanning, Guangxi, 530021, China

  • Gustave Roussy - Departement Oncologie-Radiotherapie

    ACTIVE_NOT_RECRUITING

    Villejuif, Île-de-France Region, 94800, France

  • Gyeongsang National University Hospital | Oncology

    NOT_YET_RECRUITING

    Jinju, Gyeongsangnam-do, 52727, South Korea

  • HFR Freiburg - Kantonsspital

    NOT_YET_RECRUITING

    Fribourg, 1708, Switzerland

  • Harbin Medical University Cancer Hospital

    WITHDRAWN

    Harbin, Heilongjiang, 150000, China

  • Hokkaido University Hospital

    RECRUITING

    Sapporo, Hokkaido, 060-8648, Japan

  • Hong Kong United Oncology Centre

    ACTIVE_NOT_RECRUITING

    Kowloon, 00000, Hong Kong

  • Hopital Foch - Oncologie digestive et thoracique

    WITHDRAWN

    Suresnes, Île-de-France Region, 92150, France

  • Hopital La Cavale Blanche - CHU de Brest - institut de cancerologie et d'imagerie

    ACTIVE_NOT_RECRUITING

    Brest, Brittany Region, 29200, France

  • Hopital Nord Laennec - Oncologie medicale thoracique et digestive

    ACTIVE_NOT_RECRUITING

    Nantes, Pays de la Loire Region, 44093, France

  • Hospital Clinic De Barcelona | Oncologia

    WITHDRAWN

    Barcelona, 08036, Spain

  • Hospital General Universitario Gregorio Maranon | Oncologia

    WITHDRAWN

    Madrid, 28009, Spain

  • Hospital Germans Trias I Pujol | Oncologia

    ACTIVE_NOT_RECRUITING

    Badalona, Barcelona, 08916, Spain

  • Hospital Italiano de Buenos Aires

    WITHDRAWN

    Buenos Aires, C1199ABB, Argentina

  • Hospital Pedro Hispano | Clinical Research Center

    RECRUITING

    Matosinhos Municipality, Porto District, 4464-513, Portugal

  • Hospital Sirio Libanes

    RECRUITING

    São Paulo, 01308-050, Brazil

  • Hospital Sirio-Libanes (HSL) - Centro de Oncologia - Brasilia

    NOT_YET_RECRUITING

    São Paulo, 71635-610, Brazil

  • Hospital Universitari Dexeus Grupo Quironsalud | Oncologia

    ACTIVE_NOT_RECRUITING

    Barcelona, 08028, Spain

  • Hospital Universitari Vall D Hebron | Oncologia

    ACTIVE_NOT_RECRUITING

    Barcelona, 08035, Spain

  • Hospital Universitario De Navarra | Oncologia

    ACTIVE_NOT_RECRUITING

    Pamplona, Navarre, 31008, Spain

  • Hospital Universitario Fundacion Jimenez Diaz | Oncologia

    WITHDRAWN

    Madrid, 28040, Spain

  • Hospital Universitario Puerta De Hierro De Majadahonda | Oncologia

    ACTIVE_NOT_RECRUITING

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario Ramon Y Cajal | Oncologia

    WITHDRAWN

    Madrid, 28034, Spain

  • Hospital Universitario Y Politecnico La Fe | Oncologia

    ACTIVE_NOT_RECRUITING

    Valencia, 46026, Spain

  • Hospital Universitrio Dr. José Eleuterio González. Servicio de Oncologia

    RECRUITING

    Monterrey, 64460, Mexico

  • Hospital de Base | Funfarme - Centro Integrado de Pesquisa - Cardiologia

    WITHDRAWN

    São José do Rio Preto, São Paulo, 15090-000, Brazil

  • Hubei Cancer Hospital

    ACTIVE_NOT_RECRUITING

    Wuhan, Hubei, 430079, China

  • Humanitas Mirasole S.p.A. - Oncologia Medica ed Ematologia

    ACTIVE_NOT_RECRUITING

    Rozzano, 20089, Italy

  • Hunan Cancer Hospital - Oncology Department

    ACTIVE_NOT_RECRUITING

    Changsha, Hunan, 410013, China

  • I.F.O. Istituti Fisioterapici Ospitalieri_Ospedale Regina Elena -- Oncologia Medica 2

    ACTIVE_NOT_RECRUITING

    Roma, 00144, Italy

  • IPO Porto

    RECRUITING

    Porto, 4200-072, Portugal

  • Institut Bergonie - Unicancer Nouvelle Aquitaine

    ACTIVE_NOT_RECRUITING

    Bordeaux, New Aquitaine, 33076, France

  • Institut Coeur Poumon CHRU Lille - Pole Cardio-vasculaire et pulmonaire

    ACTIVE_NOT_RECRUITING

    Lille, Hauts-de-France, 59000, France

  • Institut Curie - Paris - Oncologie medicale

    ACTIVE_NOT_RECRUITING

    Paris, Île-de-France Region, 75248, France

  • Institut de Cancerologie Ouest - Saint-Herblain

    ACTIVE_NOT_RECRUITING

    Saint-Herblain, Pays de la Loire Region, 44800, France

  • Instituto Argentino de Diagnostico y Tratamiento (IADT)

    WITHDRAWN

    TBC, Buenos Aires, B1841, Argentina

  • Instituto Nacional de Cancerología

    RECRUITING

    Mexico City, Mexico City, 14080, Mexico

  • Institutul Oncologic Prof. Dr. Alexandru Trestioreanu (IOB); Oncologie Medicală II

    ACTIVE_NOT_RECRUITING

    Bucharest, 22328, Romania

  • Institutul Oncologic Prof. Dr. Ion Chiricuta

    ACTIVE_NOT_RECRUITING

    Cluj-Napoca, 400015, Romania

  • Instytut Gruzlicy i Chorob Pluc

    WITHDRAWN

    Warsaw, 01-138, Poland

  • Irmandade Santa Casa de Misericordia de Porto Alegre | Oncology

    RECRUITING

    São Paulo, 90020-090, Brazil

  • Istituto Europeo di Oncologia s.r.l - Oncologia Toracica

    ACTIVE_NOT_RECRUITING

    Milan, 20141, Italy

  • Istituto Oncologico Veneto_Padova - UOC Oncologia 2

    ACTIVE_NOT_RECRUITING

    Padova, 35128, Italy

  • Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori IRST S.r.l. - GDP Toracica

    ACTIVE_NOT_RECRUITING

    Meldola, 47014, Italy

  • Jewish General Hospital | Pulmonary Oncology

    RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

  • Jiangsu Provincial People's Hospital - The First Affiliated Hospital of Nanjing Medical University

    ACTIVE_NOT_RECRUITING

    Nanjing, Jiangsu, 210029, China

  • Jilin Cancer Hospital

    ACTIVE_NOT_RECRUITING

    Changchun, Jilin, 130000, China

  • John B. Amos Cancer Center

    RECRUITING

    Columbus, Georgia, 31904, United States

  • Kansai Medical University Hospital

    ACTIVE_NOT_RECRUITING

    Hirakata, Osaka, 573-1191, Japan

  • Kantonsspital Baden

    ACTIVE_NOT_RECRUITING

    Baden, Canton of Aargau, 5404, Switzerland

  • Kaohsiung Medical University Chung-Ho Memorial Hospital

    RECRUITING

    Kaohsiung City, 807377, Taiwan

  • Kindai University Hospital

    NOT_YET_RECRUITING

    Sakai, Osaka, 590-0197, Japan

  • Kitasato University Hospital

    ACTIVE_NOT_RECRUITING

    Sagamihara, Kanagawa, 252-0375, Japan

  • Klinik Floridsdorf, Pneumo-onkologische Ambulanz und Tagesklinik

    ACTIVE_NOT_RECRUITING

    Vienna, 1210, Austria

  • Kliniken der Stadt Köln gGmbH - Krankenhaus Merheim - Lungenklinik

    ACTIVE_NOT_RECRUITING

    Cologne, North Rhine-Westphalia, 51109, Germany

  • Klinikum Nürnberg - Klinik für Innere Medizin 3, Schwerpunkt Pneumologie (Lungenheilkunde)

    ACTIVE_NOT_RECRUITING

    Nuremberg, Bavaria, 90419, Germany

  • Kobe University Hospital

    ACTIVE_NOT_RECRUITING

    Kobe, Hyōgo, 650-0017, Japan

  • Komarom-Esztergom Varmegyei Szent Borbala Korhaz

    WITHDRAWN

    Tatabánya, Komárom-Esztergom, 2800, Hungary

  • Krajská nemocnice T. Bati - Pneumoonkologická a klinická onkologie

    WITHDRAWN

    Zlín, Zlín, 762 75, Czechia

  • Kyiv City Clinical Oncology Center - Department of Chemotherapy #1

    NOT_YET_RECRUITING

    Kyiv, 03115, Ukraine

  • LLC "RDP Ukraine" - Medical Department

    NOT_YET_RECRUITING

    Dnipro, 49102, Ukraine

  • Liga Norte Riograndense Contra o Cancer | Centro de Pesquisa Clínica

    RECRUITING

    Natal, Rio Grande do Norte, 59040-000, Brazil

  • Limited Liability Company "MedOffice Group Medical Center"

    ACTIVE_NOT_RECRUITING

    Kyiv, 03189, Ukraine

  • LinYi Cancer Hospital (Linyi Tumor Hospital)

    ACTIVE_NOT_RECRUITING

    Linyi, Shandong, 276001, China

  • Lungenklinik Hemer, Thorakale Onkologie und onkologische Palliativmedizin

    ACTIVE_NOT_RECRUITING

    Hemer, North Rhine-Westphalia, 58675, Germany

  • M Health Fairview Masonic Cancer Clinic - Clinics and Surgery Center

    NOT_YET_RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • MHAT "Heart and brain" Pleven

    NOT_YET_RECRUITING

    Pleven, Pleven Province, 5804, Bulgaria

  • MHAT Park Hospital EOOD

    WITHDRAWN

    Plovdiv, Plovdiv Province, 4109, Bulgaria

  • MHAT Serdikamed

    ACTIVE_NOT_RECRUITING

    Sofia, Sofia City Province, 1303, Bulgaria

  • MHAT Sveta Marina EAD

    NOT_YET_RECRUITING

    Varna, Varna Province, 9010, Bulgaria

  • MHAT Uni Hospital

    NOT_YET_RECRUITING

    Panagyurishte, Pazardzhik Province, 4500, Bulgaria

  • MNCE "Uzhhorod City Multidisciplinary Clinical Hospital" -Oncology Department

    NOT_YET_RECRUITING

    Uzhhorod, 88000, Ukraine

  • Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi

    COMPLETED

    Istanbul, 34899, Turkey (Türkiye)

  • Masarykova Univerzita - Masarykuv Onkologicky Ustav (MOU) - Klinika Komplexni Onkologicke Pece (KKOP)

    RECRUITING

    Brno, South Moravian, 602 00, Czechia

  • Mazowieckie Centrum Leczenia Chorob Pluc i Gruzlicy w Otwocku

    WITHDRAWN

    Otwock, 05-400, Poland

  • Medical Center LLC "Verum Expert Clinic"

    NOT_YET_RECRUITING

    Kyiv, 3039, Ukraine

  • Medizinische Universität Wien Universitätsklinik f. Innere Medizin I Klinische Abteilung für Onkologie

    NOT_YET_RECRUITING

    Vienna, State of Vienna, 1090, Austria

  • Memorial Cancer Institute at Miramar

    COMPLETED

    Miramar, Florida, 33029, United States

  • Metropolitan Hospital- 4th Oncology Clinic

    WITHDRAWN

    Piraeus, 18547, Greece

  • Moffitt Cancer Center - Magnolia Campus

    NOT_YET_RECRUITING

    Tampa, Florida, 33612, United States

  • Multiprofile Hospital for Active Treatment "Sveta Sofia"

    RECRUITING

    Sofia, Sofia City Province, 1404, Bulgaria

  • Municipal Enterprise Rivne Regional Antitumor Center of the Rivne Regional Council, Abdominal department

    ACTIVE_NOT_RECRUITING

    Rivne, 33010, Ukraine

  • NAIC - Instituto do Cancer

    RECRUITING

    Bauru, São Paulo, 17033-490, Brazil

  • NJ Drum Tower Hospital, the Affil Hos of NJ Univ Med School

    ACTIVE_NOT_RECRUITING

    Nanjing, Jiangsu, 210008, China

  • NSW Health - Blacktown Hospital

    ACTIVE_NOT_RECRUITING

    Blacktown, New South Wales, 2148, Australia

  • Narodowy Instytut Onkologii-im. Marii Sklodowskiej-Curie Panstwowy Instytut Badawczy - Nowotworow Pluca i Klatki Piersiowej

    WITHDRAWN

    Warsaw, Masovian Voivodeship, 02-781, Poland

  • National Cancer Center Hospital East

    ACTIVE_NOT_RECRUITING

    Kashiwa, Chiba, 277-8577, Japan

  • National Cancer Center Singapore - Oncology Department

    ACTIVE_NOT_RECRUITING

    Singapore, 168583, Singapore

  • National Cheng Kung University Hospital

    RECRUITING

    Tainan, 704, Taiwan

  • National Hospital Organization Himeji Medical Center

    NOT_YET_RECRUITING

    Himeji, Hyōgo, 670-8520, Japan

  • National Hospital Organization Kyushu Medical Center

    ACTIVE_NOT_RECRUITING

    Fukuoka, 810-8563, Japan

  • National Hospital Organization Nagoya Medical Center

    ACTIVE_NOT_RECRUITING

    Nagoya, Aichi-ken, 460-0001, Japan

  • National Hospital Organization-Yamaguchi-Ube Medical Center (Sanyo Hospital)

    ACTIVE_NOT_RECRUITING

    Ube, Yamaguchi, 755-0241, Japan

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 100, Taiwan

  • National Taiwan University Hospital (NTUH) - Cancer Research Center

    RECRUITING

    Taipei, 100225, Taiwan

  • Nederlands Kanker Instituut

    ACTIVE_NOT_RECRUITING

    Amsterdam, North Holland, 1066 CX, Netherlands

  • Nemocnice AGEL Nový Jičín a.s. - Oddělení radioterapie a onkologie

    WITHDRAWN

    Nový Jičín, Moravian-Silesian Region, 741 01, Czechia

  • Nemocnice AGEL Ostrava-Vítkovice a. s. - Plicní oddělení

    WITHDRAWN

    Ostrava - Vítkovice, Moravian-Silesian Region, 703 00, Czechia

  • Niigata Cancer Center Hospital

    ACTIVE_NOT_RECRUITING

    Niigata, 951-8566, Japan

  • Nippon Medical School - Nippon Medical School Hospital - Cancer Center

    NOT_YET_RECRUITING

    Bunkyo-ku, Tokyo, 113-8603, Japan

  • Norrlands Universitetssjukhus Umeå - Cancercentrum

    COMPLETED

    Umeå, Västerbotten County, 901 85, Sweden

  • ONCARE Treatment Center

    RECRUITING

    San Pedro Garza García, 66220, Mexico

  • Odense University Hospital | Svendborg Sygehus - Oncology Department

    ACTIVE_NOT_RECRUITING

    Odense, Region of Southern Denmark / Region Syddanmark, 5000, Denmark

  • Oncare Viaducto Nápoles

    RECRUITING

    Mexico City, 3810, Mexico

  • OncoCare Cancer Centre | Gleneagles Medical Centre

    ACTIVE_NOT_RECRUITING

    Singapore, 258499, Singapore

  • Oncocenter

    NOT_YET_RECRUITING

    Timișoara, 300166, Romania

  • Oncología Integral Satélite

    RECRUITING

    Naucalpan, 53100, Mexico

  • Osaka International Cancer Institute

    ACTIVE_NOT_RECRUITING

    Osaka, 541-8567, Japan

  • Ospedale San Raffaele s.r.l. - Oncologia Medica

    COMPLETED

    Milan, 20132, Italy

  • Ospedale Vito Fazzi Lecce - Oncologia

    WITHDRAWN

    Lecce, 73100, Italy

  • POKO Poprad s.r.o.

    WITHDRAWN

    Poprad, Presov, 058 01, Slovakia

  • Patty & George Hoag Cancer Center

    WITHDRAWN

    Newport Beach, California, 92663, United States

  • Piedmont Healthcare - Atlanta

    RECRUITING

    Atlanta, Georgia, 30318, United States

  • Prince of Wales Hospital

    RECRUITING

    Hong Kong, Hong Kong SAR, 00000, Hong Kong

  • Princess Margaret Cancer Centre | Medical Oncology and Hematology

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

  • Private Enterprise Private Production Company "Acinus", Treatment and Diagnostic Center

    NOT_YET_RECRUITING

    Kropyvnytskyi, 25006, Ukraine

  • Profound Research - OMG - Royal Oak Cancer Center

    WITHDRAWN

    Royal Oak, Michigan, 48073, United States

  • Profound Research -OMG - TriAtria Cancer Center

    WITHDRAWN

    Farmington Hills, Michigan, 48334, United States

  • Pronutrir Fortaleza - CE

    RECRUITING

    Fortaleza, Ceará, 60810-180, Brazil

  • Providence Cancer Institute - Franz Clinic

    NOT_YET_RECRUITING

    Portland, Oregon, 97213, United States

  • Providence Oncology and Hematology Care Clinic Westside

    NOT_YET_RECRUITING

    Portland, Oregon, 97225, United States

  • Pusan National University Yangsan Hospital | Pulmonology

    RECRUITING

    Yangsan, Gyeongsangnam-do, 50612, South Korea

  • Queen Elizabeth Hospital Hong Kong

    RECRUITING

    Hong Kong, Hong Kong SAR, 00000, Hong Kong

  • Queen Mary Hospital

    NOT_YET_RECRUITING

    Hong Kong, Hong Kong SAR, 00000, Hong Kong

  • R.J. Zuckerberg Cancer Center

    WITHDRAWN

    New Hyde Park, New York, 11042, United States

  • Radboud University Medical Center | Afdeling Interne Geneeskunde

    WITHDRAWN

    Nijmegen, Gelderland, 6500 HB, Netherlands

  • Radiotherapy Center Cluj SRL

    ACTIVE_NOT_RECRUITING

    Florești, Comuna Floresti, 407280, Romania

  • Raffles Cancer Centre

    COMPLETED

    Singapore, 188770, Singapore

  • Rede DoR Recife - PE

    RECRUITING

    Recife, Pernambuco, 50070-480, Brazil

  • Regional Medical Oncology Centre_Oncology Chemotherapy Department

    NOT_YET_RECRUITING

    Lutsk, 43018, Ukraine

  • Regionshospitalet Gødstrup - Medicinsk afdeling

    WITHDRAWN

    Herning, Central Denmark Region / Region Midtjylland, 7400, Denmark

  • Rigshospitalet Copenhagen University Hospital | Oncology Department

    ACTIVE_NOT_RECRUITING

    Copenhagen, Capital Region / Region Hovedstaden, 2100, Denmark

  • Robert Bosch Krankenhaus - Haematologie, Onkologie und Palliativmedizin

    COMPLETED

    Stuttgart, Baden-Wurttemberg, 70376, Germany

  • Royal Surrey County Hospital | Cancer Centre

    RECRUITING

    Guildford, Surrey, GU2 7XX, United Kingdom

  • S.C Ovidius Clinical Hospital SRL - Oncology Department

    NOT_YET_RECRUITING

    Ovidiu, 905900, Romania

  • Saitama Cancer Center

    ACTIVE_NOT_RECRUITING

    Kitaadachi, Saitama, 362-0806, Japan

  • Sakarya Universitesi Egitim ve Arastirma Hastanesi

    NOT_YET_RECRUITING

    Sakarya, 54100, Turkey (Türkiye)

  • Samsung Medical Center | Oncology

    RECRUITING

    Seoul, 06351, South Korea

  • Sc Oncolab Srl

    NOT_YET_RECRUITING

    Craiova, Dolj, 200385, Romania

  • Sendai Kousei Hospital

    ACTIVE_NOT_RECRUITING

    Sendai, Miyagi, 980-0873, Japan

  • Seoul National University Hospital | Oncology

    RECRUITING

    Jongno -Gu, Seoul, 03080, South Korea

  • Severance Hospital | Oncology

    RECRUITING

    Seoul, 03722, South Korea

  • Shaare Zedek Medical Center (SZMC)

    ACTIVE_NOT_RECRUITING

    Jerusalem, 91031, Israel

  • Shandong University - Shandong Cancer Hospital

    ACTIVE_NOT_RECRUITING

    Jinan, Shandong, 250117, China

  • Shanghai Chest Hospital, Shanghai Jiaotong University

    ACTIVE_NOT_RECRUITING

    Shanghai, Shanghai Municipality, 200030, China

  • Sir Run Run Shaw Hospital, Zhejiang Univ. School of Medicine - Oncology Department

    ACTIVE_NOT_RECRUITING

    Hangzhou, Zhejiang, 310016, China

  • Skånes Universitetssjukhus - Lund - Lungmedicin

    ACTIVE_NOT_RECRUITING

    Lund, 221 85, Sweden

  • Soroka Medical Center- Legacy Heritage Cancer Center

    COMPLETED

    Beersheba, 8410101, Israel

  • Specialized Hospital for Active Treatment of Oncology

    WITHDRAWN

    Sofia, Sofia City Province, 1797, Bulgaria

  • Spitalul Clinic Coltea

    COMPLETED

    Bucharest, 30171, Romania

  • St Vincent's Hospital | Oncology

    NOT_YET_RECRUITING

    Suwon, Gyeonggi-do, 16247, South Korea

  • Sunway Medical Centre

    ACTIVE_NOT_RECRUITING

    Subang Jaya, Selangor, 47500, Malaysia

  • Sunway Medical Centre Penang

    ACTIVE_NOT_RECRUITING

    Perai, Pulau Pinang, 13700, Malaysia

  • Swietokrzyskie Centrum Onkologii

    COMPLETED

    Kielce, 25-734, Poland

  • Taichung Veterans General Hospital

    RECRUITING

    Taichung, 40705, Taiwan

  • Taipei Veterans General Hospital

    RECRUITING

    Taipei, 11217, Taiwan

  • Tan Tock Seng Hospital

    COMPLETED

    Singapore, 308433, Singapore

  • Taylor Cancer Research Center

    RECRUITING

    Maumee, Ohio, 43537, United States

  • Tel- Aviv Sourasky Medical Center - Nephrology

    COMPLETED

    Tel Aviv, 6423906, Israel

  • The Oncology Institute of Hope and Innovation - Fort Lauderdale 17th Street

    RECRUITING

    Fort Lauderdale, Florida, 33316, United States

  • The People's Liberation Army General Hospital (Beijing 301 Hospital)

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100853, China

  • The University of Chicago Medical Center - Hyde Park - Hematology & Oncology

    WITHDRAWN

    Chicago, Illinois, 60637, United States

  • The University of Texas MD Anderson Cancer Center - Texas Medical Center

    RECRUITING

    Houston, Texas, 77030, United States

  • The first Affiliated Hospital of Guangzhou Medical University

    ACTIVE_NOT_RECRUITING

    Guangzhou, Guangdong, 510230, China

  • Thoracic General Hospital Of Athens I Sotiria-3rd University Department of Internal Medicine

    ACTIVE_NOT_RECRUITING

    Athens, 11527, Greece

  • Toowoomba Hospital Oncology Clinical Trials

    WITHDRAWN

    Toowoomba, Queensland, 4350, Australia

  • Torbay Hospital | Oncology

    RECRUITING

    Torquay, Devon, TQ2 7AA, United Kingdom

  • Tottori University Hospital

    ACTIVE_NOT_RECRUITING

    Yonago, Tottori, 683-8504, Japan

  • Turku University Hospital, Turun yliopistollinen sairaala (TYKS) - Keuhkosairauksien poliklinikka

    WITHDRAWN

    Turku, Southwest Finland, 20520, Finland

  • UC Medical Center - Oncology

    RECRUITING

    Cincinnati, Ohio, 45219, United States

  • UC San Diego Health - Moores Cancer Center

    WITHDRAWN

    San Diego, California, 92037, United States

  • UCLA Health Santa Monica Cancer Care

    RECRUITING

    Santa Monica, California, 90404, United States

  • UCSF Bakar Precision Cancer Medicine Building - Thoracic Surgery and Oncology

    RECRUITING

    San Francisco, California, 94158, United States

  • UM Greenebaum Comprehensive Cancer Center

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21201, United States

  • UMass Memorial Medical Center - University Campus - Hematology/Oncology

    WITHDRAWN

    Worcester, Massachusetts, 01655, United States

  • UZ Leuven Gasthuisberg - Pneumology Department

    ACTIVE_NOT_RECRUITING

    Leuven, Flemish Brabant, 3000, Belgium

  • Unidade Local de Saúde de Coimbra, E.P.E. - Hospitais da Universidade de Coimbra - Serviço de Oncologia

    NOT_YET_RECRUITING

    Coimbra, 3004-561, Portugal

  • Uniklinikum Salzburg, Universitätsklinik für Innere Medizin III

    NOT_YET_RECRUITING

    Vienna, State of Salzburg, 1090, Austria

  • Uniklinikum Salzburg, Universitätsklinik für Pneumologie/ Lungenheilkunde

    NOT_YET_RECRUITING

    Vienna, State of Salzburg, 1090, Austria

  • Union Hospi, Tongji Med College, Huazhong Univ. Scien&Tech

    ACTIVE_NOT_RECRUITING

    Wuhan, Hubei, 430023, China

  • Universitaetsklinikum Essen - Innere Klinik (Tumorforschung)

    ACTIVE_NOT_RECRUITING

    Essen, North Rhine-Westphalia, 45147, Germany

  • Universitaetsklinikum Giessen und Marburg - Medizinische Klinik IV Organonkologie

    NOT_YET_RECRUITING

    Giessen, Hesse, 35392, Germany

  • Universiti Malaya Medical Centre

    ACTIVE_NOT_RECRUITING

    Kuala Lumpur, Kuala Lumpur, 59100, Malaysia

  • University General Hospital Attikon, 2nd Department of Propaedeutic and Internal Medicine

    ACTIVE_NOT_RECRUITING

    Athens, 12462, Greece

  • University General Hospital Attikon-4th Department of Internal Medicine

    WITHDRAWN

    Chaïdári, Attica, 12462, Greece

  • University Hospital Kebangsaan Malaysia

    WITHDRAWN

    Cheras, Kuala Lumpur and Selangor, 56000, Malaysia

  • University Hospital Simmons Cancer Center Lung/Head Neck Clinic

    WITHDRAWN

    Dallas, Texas, 75235, United States

  • University Multiprofile Hospital For Active Treatment Sofiamed OOD, Sofia

    NOT_YET_RECRUITING

    Sofia, Sofia City Province, 1797, Bulgaria

  • University of Electronic Science & Technology of China - Sichuan Cancer Hospital & Institute (Sichuan Provincial Tumor Hospital)

    ACTIVE_NOT_RECRUITING

    Chengdu, Sichuan, 610041, China

  • University of Illinois Hospital - Outpatient Cancer Care Center

    RECRUITING

    Chicago, Illinois, 60612, United States

  • University of the Sunshine Coast

    WITHDRAWN

    Buderim, Queensland, 4556, Australia

  • Universitätsklinikum Frankfurt - Medizinische Klinik II, Hämatologie und Onkologie

    NOT_YET_RECRUITING

    Frankfurt am Main, Hesse, 60590, Germany

  • Uniwersytecki Szpital Kliniczny Nr 2 Uniwersytetu Medycznego w Łodzi

    COMPLETED

    Lodz, 92-213, Poland

  • Uniwersytecki Szpital Kliniczny w Bialymstoku

    WITHDRAWN

    Bialystok, 15-276, Poland

  • Velindre Cancer Centre | Clinical Trials Unit

    NOT_YET_RECRUITING

    Cardiff, Wales, CF14 2TL, United Kingdom

  • West China Hospital Sichuan University

    ACTIVE_NOT_RECRUITING

    Chengdu, Sichuan, 610041, China

  • Wielkopolskie Centrum Pulmonologii i Torakochirurgii

    ACTIVE_NOT_RECRUITING

    Poznan, 60-569, Poland

  • Xiamen University - The First Affiliated Hospital

    COMPLETED

    Xiamen, Fujian, 361003, China

  • Zhejiang Cancer Hospital

    ACTIVE_NOT_RECRUITING

    Hangzhou, Zhejiang, 310022, China

  • Zhejiang University School of Medicine - Taizhou Hospital of Zhejiang Province

    ACTIVE_NOT_RECRUITING

    Taizhou, Jiangsu, 317000, China

  • Zhongshan Hospital, Fudan University

    ACTIVE_NOT_RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

  • hopital Emile Muller - Service Pneumologie

    WITHDRAWN

    Mulhouse, Grand Est, 68100, France

  • hopital Lyon sud HCL - Pneumologie aigue specialisee et cancerologie thoracique

    ACTIVE_NOT_RECRUITING

    Pierre-Bénite, Auvergne-Rhône-Alpes, 69310, France

  • İ.A.Ü. VM Medical Park Florya Hastanesi

    NOT_YET_RECRUITING

    Küçükçekmece, 34295, Turkey (Türkiye)

  • İstanbul Medeniyet Üniversitesi Göztepe Süleyman Yalçın Şehir Hastanesi

    ACTIVE_NOT_RECRUITING

    Kadıköy, Istanbul, 34722, Turkey (Türkiye)

  • Ηenry Dunant Hospital Center-4th Oncology Department and Clinical Trials Unit

    ACTIVE_NOT_RECRUITING

    Athens, 11526, Greece

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