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New hope for brain cancer: drug cocktail targets tough lymphoma

NCT ID NCT05698147

First seen Sep 30, 2025 · Last updated May 17, 2026 · Updated 29 times

Summary

This study tests a new three-drug combination (selinexor, methotrexate, and rituximab) for adults with central nervous system lymphoma that has returned or not responded to prior treatment. About 30 participants will receive the drugs to find the safest dose and see how well it shrinks tumors. The goal is to control the disease, not cure it, as ongoing management may still be needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beijing Tiantan Hospital, Capital Medical University

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Hematology, Huashan Hospital, Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200040, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oncology Department of The First Affiliated Hospital of Zhengzhou University

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Affiliated Hospital Of Anhui Medical University

    NOT_YET_RECRUITING

    Hefei, Anhui, China

    Contact

  • The First Affiliated Hospital Of Fujian Medical University

    NOT_YET_RECRUITING

    Fuzhou, Fujian, China

    Contact

Conditions

Explore the condition pages connected to this study.