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Brain scans reveal how face transplant patients learn to see 'Me'

NCT ID NCT03027141

Knowledge-focused Sponsor: NYU Langone Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study used brain scans (fMRI) to see how the brain adapts to a new face after a face transplant. Four people with severe facial injuries were scanned before and after surgery to track how their brain learned to recognize the new face as their own. The goal was to understand the brain's role in self-recognition, not to test a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

4 people

The number who actually took part.

Started

Feb 2017

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who have suffered from severe facial disfigurement which warrant facial transplantation and have been evaluated and approved for transplantation, will be included. Exclusion Criteria: * Must be be able to enter and be scanned using MRI. * Able to give full informed consent, before each scan and throughout their time in which they are participating in the study * Able to perform the task to a high standard and also to have no underlying conditions that may alter how they process pictures of face * Participants must have none of the following, which cannot safely be removed without risk or discomfort while they enter the MRI unit: * a pacemaker * metal implants * metal that cannot be removed on their body (e.g. shrapnel, piercings) * metal clips * an artificial heart valve * a cochlear implant * drug patches * a contraceptive coil * dental plates/braces with metal in * hearing aids * Participants will also be excluded on the grounds of safety and comfort inside the MRI scanner if they have one of the following underlying conditions * epilepsy * diabetes * heart disease * thermoregulatory problems (problems regulating body temperature) * a possibility of being pregnant * currently breastfeeding * Participants will also be excluded on the grounds of MRI data quality for the following reasons: * history of mental illness * claustrophobia (discomfort in confined spaces) * Neurological conditions

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Disfigurement of face

Contacts and locations

Locations

  • New York University School of Medicine

    New York, New York, 10016, United States