New blood thinner tested in small chinese heart study
NCT ID NCT07615868
First seen Jun 25, 2026 · Last updated Jul 15, 2026 · Updated 3 times
Summary
This early-stage trial will study how a single 16 mg dose of selatogrel, an injectable blood thinner, is absorbed and tolerated in 20 Chinese adults with chronic coronary syndrome. Participants will stay at a clinic for a few days and receive either selatogrel or a placebo. The goal is to gather safety and drug-level data, not to treat the condition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- selatogrel
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Key Inclusion Criteria: * Chronic coronary syndrome participants defined by the presence of any of the following conditions: * History of coronary artery disease with coronary artery stenosis confirmed by a coronary catheterization (at any time prior to Screening) / computed tomography (CT) angiogram ≥ 50%. * Previously documented myocardial infarction occurring more than 3 months prior to Screening. * Acetylsalicylic acid as mono antiplatelet background therapy stable for at least 1 month prior to Screening. * Minimum weight of 50.0 kg at Screening. Key Exclusion Criteria: * Known liver impairment significantly affecting the hepatic function (e.g., ascites, icterus, signs of coagulopathy). * End-stage renal failure requiring dialysis. * Treatment with another investigational small-molecule or peptide drug within 3 months or 5 × t1/2 (whichever is longer) or with an investigational antibody treatment within 6 months prior to Screening. * History of major medical or surgical disorders, which in the opinion of the investigator, are likely to interfere with the metabolism, or excretion of the trial treatment(s) (appendectomy and herniotomy allowed). * Concomitant diseases (e.g., advanced liver cirrhosis, mental illness, neurodegenerative disease, terminal malignancy, etc.) or conditions (e.g., inability to communicate well with the investigator in the local language, inability to consent) that, in the opinion of the investigator, may prevent subject from complying with study requirements or may be a confounder for the study interpretation. * Conditions associated with atherosclerosis: * Acute coronary syndrome, percutaneous coronary intervention, Coronary Artery Bypass Grafting, or any intervention for peripheral artery disease within 3 months prior to randomization. * Acute ischemic stroke or transient ischemic attack within 3 months prior to randomization * Mitigation of bleeding risks: * Active internal bleeding, or medical history of recent (\< 1 month) bleeding disorders or conditions associated with high risk of bleeding (e.g., clotting disturbances, gastrointestinal bleed, hemoptysis, or any history of intracranial bleeding). * Hemoglobin ≤ 10 g/dL at Screening. * Loss of at least 250 mL of blood within 3 months prior to Screening.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Anzhen Hospital
RECRUITINGBeijing, 100029, China
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