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New combo therapy aims to tackle Ultra-Resistant schizophrenia

NCT ID NCT05240976

First seen Mar 31, 2026 · Last updated Jun 09, 2026 · Updated 12 times

Summary

This study tests whether adding an anti-inflammatory drug to an NMDA-enhancing agent can improve thinking and memory in people with ultra-resistant schizophrenia. About 80 adults who have not responded well to clozapine will receive the combination or a placebo. The goal is to see if this approach can better control symptoms and boost cognitive function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Psychiatry, China Medical University Hospital

    RECRUITING

    Taichung, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Inflammation schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.