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Birth control implant gets a new home: the shoulder blade

NCT ID NCT07201402

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jul 28, 2026 · Updated 3 times

Summary

This study is testing whether the etonogestrel contraceptive implant can be placed under the skin near the shoulder blade instead of the usual upper arm spot. Researchers will check hormone levels and side effects in 62 women over two years. The goal is to see if this alternative site works just as well and is safe.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
etonogestrel contraceptive implant
What this could lead to
If successful, this could offer a new, convenient insertion site for the contraceptive implant, potentially improving comfort and acceptance.
What could go wrong
This is a small Phase 2 study with only 62 participants, so results may not apply to everyone. The alternative site might have different side effects or lower effectiveness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 62 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Provision of signed and dated informed consent form 2. Stated willingness to comply with all study procedures and availability for the duration of the study 3. Sex assigned at birth must be Female 4. Aged 18-45 years 5. In good general health as evidenced by medical history and no need for regular intensive medical interventions (e.g., inpatient admissions, surgical treatments). The Principal Investigator will be responsible for determining good general health for potential participants with complicated medical histories 6. Interest and willingness to use an etonogestrel contraceptive implant 7. Negative pregnancy test at the time of study enrollment and not planning to become pregnant in the next 36 months 8. Willing to abstain from medications and supplements known to induce/inhibit CYP3A (e.g., rifampin, carbamazepine, ketoconazole, St. John's wort) during the study. In the inducer/inhibitor CYP3A medication is a prescribed medication, individuals must provide the prescriber information for the PI to confirm it is safe for this medication to be abstained during the study 9. Body-mass index ≥18.5kg/m2 Exclusion Criteria: 1. Self-reported contraindications to the use of the ENG implant based on the CDC Medical Eligibility Criteria guidelines for any conditions with a category 3 or 4 recommendation 1. Current breast cancer or personal history of breast cancer 2. Malignant liver tumor (hepatocellular carcinoma) 3. Allergic reaction to any components of the ENG implant 2. Any self-reported known liver conditions that could affect drug metabolism (e.g., cirrhosis, hepatitis) 3. Personal history of deep vein thrombosis (DVT), venous thromboembolism (VTE), or arterial thromboembolism (ATE). 4. Currently taking and unable or unwilling to abstain from any medications or supplements known to be CYP3A inducers/inhibitors. 5. Current use of a progestin-only contraceptive method containing desogestrel or etonogestrel 6. History of spinal deformity (e.g., kyphosis, lordosis) 7. History of shoulder or scapular surgery on the non-dominant side 8. Non-dominant shoulder mobility limitations 9. Previous trauma to the non-dominant scapular region 10. Active skin conditions (e.g., psoriasis) in the non-dominant scapular region 11. Inability to palpate the bony landmarks of the scapula due to adiposity or other body habitus

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Colorado Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

  • Yale University School of Medicine

    RECRUITING

    New Haven, Connecticut, 06520, United States

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