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New pill aims to slow lung scarring in IPF patients

NCT ID NCT06747923

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called SB17170 in 30 adults with moderate to severe idiopathic pulmonary fibrosis (IPF), a disease that scars the lungs and makes breathing hard. Participants take either the drug or a placebo daily for 12 weeks. The main goal is to see if the drug improves lung function, measured by how much air they can exhale.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
SB17170 (an experimental oral drug)
What this could lead to
If successful, this could point toward a new treatment option to slow lung function decline in people with idiopathic pulmonary fibrosis.
What could go wrong
This is an early Phase 2a trial with only 30 participants, so results may not apply broadly. The drug may not improve lung function or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adult male/female 40 years or older at the time of obtaining informed consent 2. Patients diagnosed with idiopathic pulmonary fibrosis who meet the following criteria: * Patients with idiopathic pulmonary fibrosis who are confirmed by chest High-Resolution Computed Tomography (HRCT) scan * Patients with Usual Interstitial Pneumonia (UIP) or probable UIP HRCT pattern consistent with a diagnosis of idiopathic pulmonary fibrosis confirmed through central reading of chest HRCT before the baseline visit 3. Patients with a history of idiopathic pulmonary fibrosis treatment who meet the defined criteria 4. Patients with Forced Vital Capacity (FVC) ≥ 45% of the normal predicted value at the screening visit 5. Patients meeting pulmonary function test criteria at the screening visit 6. Patients who have received the explanation of this clinical trial and voluntarily agreed and signed the informed consent form Exclusion Criteria: 1. When there is a primary disease showing UIP patterns (rheumatoid arthritis-related interstitial lung disease, connective tissue disease-related interstitial lung disease, etc.) and/or other clinically significant lung abnormalities 2. Patients with confirmed acute exacerbation of IPF within 6 months prior to screening and/or during the screening period 3. Patients with lower respiratory tract infections requiring antibiotic treatment 4. Patients who underwent major surgery within 3 months before screening or have major surgery planned during the clinical trial 5. Patients with a history of malignancy or documented evidence of active or suspected malignancy within 5 years prior to screening 6. Patients with evidence of active infection 7. Patients with the following cardiovascular and cerebrovascular diseases at the time of screening: * Severe hypertension within 3 months * Myocardial infarction or unstable angina within 6 months * History of thrombotic events within 6 months * Diagnosis of heart failure within 6 months 8. Patients with pulmonary hypertension 9. Patients who are unable to take drugs orally or have a history of major gastrointestinal surgery or pathological findings that may affect the absorption of the investigational product 10. Patients with Human Immunodeficiency Virus (HIV) infection or active hepatitis B or C

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    5 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ajou University Hospital

    NOT_YET_RECRUITING

    Suwon, South Korea

  • Chung-Ang University Gwangmyeong Hospital

    RECRUITING

    Gwangmyeong, South Korea

  • Myong Ji Hospital

    RECRUITING

    Goyang, South Korea

  • Seoul Asan Hospital

    NOT_YET_RECRUITING

    Seoul, South Korea

  • The Catholic Univ. of Korea Seoul St. Mary's Hospital

    NOT_YET_RECRUITING

    Seoul, South Korea

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