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Why do some seniors stop eating? scientists investigate

NCT ID NCT07636369

Knowledge-focused Sponsor: Singapore Institute of Food and Biotechnology Innovation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why some older adults lose their appetite while others keep a healthy one. Researchers will measure how taste, digestion, and hormones differ between the two groups. Twenty women aged 65-74 will take part. No treatment is given; the goal is simply to learn more about the causes of appetite decline in aging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 to 74 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Postmenopausal female * Aged 65-74 years * Habitual breakfast consumer (consumes breakfast between 7am to 10am) * Willingness to consume meals and follow intervention protocol * English speaking Exclusion Criteria: * BMI ≥ 27.5 * Diagnosed with medical condition that may influence appetite or microbiome (e.g. diabetes, thyroid disorders, gastrointestinal diseases) * Currently taking any medications or supplements that may influence appetite or the microbiome (e.g. probiotics, antibiotics, appetite stimulants/suppressants) one month prior to their first visit in consultation with study physician, PI and study team * Following a special diet for weight management (e.g. low-calorie, low carbohydrate) * History of bariatrics surgery * Intentional attempt to change body weight or composition * History of severe vasovagal syncope (blackouts or near faints) following blood draw * Drug abuse within last 5 years * Excessive alcoholic beverage consumption \> 2 servings per day (1 serving defined as 360 mL beer, 150 mL wine or 45 mL distilled spirits) * Smoking (cigarette, e-cigarette, cigar, pipe, vape) * Engaging in habitual vigorous physical activity (as defined by physical activity questionnaire-PAQ) * Loose teeth or jaw pain * Not missing \> 2 non-wisdom molars * Involvement in other clinical studies that may influence the outcome of the study * A study team member or their immediate family member

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Conditions

The condition(s) this trial relates to.

Malnutrition nutritional deficiency disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anorexia of aging Malnutrition or risk of malnutrition

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clinical Nutrition Research Centre

    Singapore, Singapore

More trials for these conditions

Other studies related to the condition(s) this trial covers.