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Knee surgery may help reverse Age-Related muscle decline

NCT ID NCT06635356

Knowledge-focused Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looked at whether knee replacement surgery can improve sarcopenia, a condition where people lose muscle mass and strength as they age. Researchers measured calf size, grip strength, and body composition in 37 patients before and after surgery. The goal was to see if the surgery and recovery process help rebuild muscle.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

37 people

The number who actually took part.

Started

Oct 2024

Finished

Apr 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Female or male patients between the ages of 50-75 who underwent knee arthroplasty surgery in orthopedic clinics in Istanbul

Ages

50 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being between 50-75 years old * Undergoing knee arthroplasty surgery * Patients who agreed to participate in the study and gave written consent Exclusion Criteria: * Having a history of malignancy * Being under 50 and over 75 years old * Having one of the muscle/nerve diseases

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Conditions

The condition(s) this trial relates to.

Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Knee arthroplasty, total Knee prosthesis Sarcopenia

Contacts and locations

Locations

  • Istanbul Physical Medicine Rehabilitation Training and Research Hospital

    Istanbul, 34192, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.