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First-in-Human trial tests implant to stop Cancer's return after surgery

NCT ID NCT04619056

Summary

This first-in-human study tested the safety of a special drug-coated membrane placed in the surgical area immediately after removing a recurring or advanced abdominal soft tissue sarcoma. The goal was to see if leaving this slow-release chemotherapy implant where the tumor was could help prevent the cancer from coming back locally. The study involved 21 patients and focused on finding the highest safe dose of the drug (SN-38) for future research.

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Contacts and locations

Locations

  • Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • Hospital General Universitario Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital Universitario Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario y Politécnico La Fe

    Valencia, 46026, Spain

  • Hospital de la Santa Creu i Sant Pau

    Barcelona, Catalonia, 08041, Spain

Conditions

Explore the condition pages connected to this study.