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Salt sensitivity in kidney disease: a new clue from uromodulin?

NCT ID NCT06363097

Knowledge-focused Sponsor: Aristotle University Of Thessaloniki Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how salt in the diet affects blood pressure in 130 adults with chronic kidney disease. Researchers measured a protein called uromodulin in urine to see if it predicts salt sensitivity. The goal was to understand why some patients' blood pressure rises more with salt, which could lead to better dietary advice.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dietary sodium (salt)
What this could lead to
If successful, this could help personalize salt intake recommendations for kidney disease patients to better control blood pressure.
What could go wrong
This is a completed observational study, not a treatment trial. Results may not lead to immediate clinical changes and need further validation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

130 people

The number who actually took part.

Started

Sep 2023

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study includes patients with CKD across all consecutive pre-dialysis stages.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥18 years 2. CKD defined based on the KDIGO criteria 3. Provision of informed written consent Exclusion Criteria: 1. Kidney transplantation or end-stage kidney disease (ESKD) under hemodialysis or peritoneal dialysis 2. Chronic atrial fibrillation or other diagnosed arrhythmia intervening with a proper 24-hour ABPM recording 3. Inability to reliably complete the study questionnaires 4. Pregnancy

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney disease Hypertension

Contacts and locations

Locations

  • 1st Department of Nephrology

    Thessaloniki, Central Macedonia, 54642, Greece

More trials for these conditions

Other studies related to the condition(s) this trial covers.