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Could a simple salt water soak ease radiation skin pain?

NCT ID NCT07553260

Symptom relief Sponsor: King Hussein Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether daily soaks with normal saline (salt water) can reduce severe skin reactions caused by radiation therapy. About 150 adults with head and neck cancer or sarcoma will either get standard care or standard care plus a 5-10 minute saline soak each day. Researchers will check if the soaks lower the chance of grade 2 or higher skin burns and help wounds heal faster.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
normal saline (0.9% sodium chloride) solution soaks
What this could lead to
If it works, this could offer a simple, low-cost way to ease painful skin reactions during radiation therapy.
What could go wrong
This is a small, early-stage trial with no prior strong evidence. The benefit may be small or none, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Eastern Cooperative Oncology Group (ECOG) performance status 0-1 * Patients receiving definitive radiotherapy for sarcomas or head and neck cancer (primary or postoperative treatment) * Planned radiation dose between 60-70 Gy according to disease-specific protocols * No prior history of malignancy other than sarcomas * Ability and willingness to comply with study procedures (\>90% expected adherence) * Signed informed consent Exclusion Criteria: * Patients receiving palliative radiotherapy * Known pre-existing skin disorders affecting radiation area (e.g., systemic lupus erythematosus, scleroderma) * ECOG performance status ≥2 * Previous radiotherapy to the same treatment field * Any condition that, in the investigator's judgment, may interfere with participation or wound healing assessment

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms radiodermatitis sarcoma skin disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute radiation dermatitis Head and neck cancer (H&N) Sarcomas

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • King Hussien Cancer Center

    Amman, Al-Jubeiha, 11941, Jordan

More trials for these conditions

Other studies related to the condition(s) this trial covers.