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Brain scans reveal how experimental drug interacts with ketamine

NCT ID NCT03770780

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 27 times

Summary

This early-stage study tested an experimental drug called SAGE-718 in 19 healthy adults to see how it affects brain chemicals when combined with ketamine. Participants received both the drug and a placebo at different times, and brain scans measured changes in key chemicals. The goal was to gather safety data and understand the drug's effects on the brain, not to treat any disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sage Investigational Site

    Long Beach, California, 90806, United States

  • Sage Investigational Site

    Berlin, New Jersey, 08009, United States

Conditions

Explore the condition pages connected to this study.