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New drug trial targets liver scarring in MASH patients

NCT ID NCT06903065

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 27 times

Summary

This early-stage study tests a new medicine called RO7790121 in 50 adults with advanced liver scarring from MASH (a type of fatty liver disease). The main goal is to check safety and how the drug moves through the body. Participants must have severe fibrosis (stage F3 or F4) and a stable weight. This is not a cure; it aims to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Adobe Clinical Research, LLC

    Tucson, Arizona, 85712, United States

  • Bellaire Clinical Research, LLC

    Bellaire, Texas, 77401, United States

  • Centro de Investigacion y Gastroenterologia

    Mexico City, Mexico CITY (federal District), 06700, Mexico

  • DHR Health Institute for Research and Development

    Edinburg, Texas, 78539, United States

  • Delta Research Partners, LLC (Bastrop)

    Bastrop, Louisiana, 71220, United States

  • FDI Clinicial Research - Mayaguez

    Mayagez, 00680, Puerto Rico

  • Fundacion Santos Y De La Garza Evia IBP

    San Pedro Garza García, Nuevo León, 66278, Mexico

  • Fundacion de Investigacion de Diego

    San Juan, 00927, Puerto Rico

  • GI Alliance

    Southlake, Texas, 76092, United States

  • Gastrointestinal Specialists of Georgia, PC

    Marietta, Georgia, 30060, United States

  • Innovative Clinical Research

    Clarksville, Tennessee, 37040, United States

  • Jubilee Clinical Research NV, LLC

    Las Vegas, Nevada, 89106, United States

  • Pinnacle Clinical Research - Austin

    Austin, Texas, 78757, United States

  • Pinnacle Clinical Research Georgetown

    Georgetown, Texas, 78626, United States

  • Pinnacle Clinical Research, PLLC

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.