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New eye injection aims to slow genetic blindness

NCT ID NCT06461286

First seen Jan 26, 2026 · Last updated Jun 19, 2026 · Updated 17 times

Summary

This study tests a new medicine called PYC-001, given as an injection into the eye, for people with a genetic condition that damages the optic nerve (OPA1 optic atrophy). The main goal is to check if the treatment is safe and tolerable. About 18 adults will receive a single dose, and researchers will monitor for side effects and any changes in vision.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Center for Eye Research Australia (CERA)

    East Melbourne, Victoria, 3002, Australia

  • Save Sight Institute - Sydney Eye Hospital

    Sydney, New South Wales, 2000, Australia

Conditions

The condition(s) this trial relates to.

autosomal dominant optic atrophy autosomal dominant optic atrophy, classic form hereditary optic atrophy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.