Baby stem cells injected to fix failing hearts in kids and young adults

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Phase 1A: Age greater than or equal to 16 years and less than 40 years (≥16 years, \<40 years). * Phase 1B: Age greater than or equal to 4 years and less than 16 years (≥4 years, \<16 years) * Subjects must be able to sign their own consent for Phase 1A of the study. * Diagnosis of dilated cardiomyopathy (DCM) defined as * Any Congenital Cardiac Malformation with systemic ventricular systolic dysfunction; Idiopathic Cardiomyopathy; Familial/Inherited and/or Genetic Cardiomyopathy; History of Myocarditis; Acquired (Chemotherapy, Iatrogenic, Infection, Rheumatic, Nutritional); Ischemic (e.g. Kawasaki Disease, post-operative); Left ventricular noncompaction; Coronary Artery Disease * Left ventricular ejection fraction less than or equal to 45% documented by two-dimensional echocardiogram or cardiac MRI within the prior six months. * Left ventricular dilation as defined by echocardiography left ventricular and end-diastolic dimension Z score \> +2.0 * Biventricular physiology with systemic left ventricle * Must receive guideline directed heart failure as defined by the American Heart Association, American College of Cardiology, and Heart Failure Society of America 118 * Have been unresponsive or poorly responsive to at least 3 months of maximum guideline directed treatments. Exclusion Criteria * Listed for heart transplantation (as UNOS status 1A) or hospitalized while waiting for transplant (while on inotropes or with ventricular assist device) * Cardiovascular surgery of percutaneous intervention to palliate or correct congenital cardiovascular malformations within 3 months of the screening visit. Patients anticipated to undergo corrective heart surgery during the 12 months after entry into Part 1A/1B. * Previous heart transplant recipient * Unoperated primary obstructive or severe regurgitant valve (aortic, pulmonary, mitral or tricuspid) disease, or significant systemic ventricular outflow obstruction or aortic arch obstruction anticipated to require surgical or transcatheter intervention within 6 months. * Restrictive or hypertrophic cardiomyopathy * Cardiogenic shock * Currently on extracorporeal membrane oxygenation support * Ventricular assist device support * Lethal, uncontrollable arrhythmia defined as an arrhythmia resulting in hemodynamic instability requiring need for defibrillation, continuous intravenous anti-arrhythmic medication or mechanical circulatory support * Patients with persistent atrial fibrillation requiring specific pharmacotherapy * Amyloidosis * Ischemic dilated cardiomyopathy * Clinical history of malignant neoplasm within 5 years (with the exception of curatively treated basal cell carcinoma, squamous cell carcinoma, or cervical carcinoma) * Serious neurologic disorder including loss of vision, stroke, or paralysis * High-grade pulmonary embolism requiring interventional catheter procedure or pulmonary hypertension requiring use of pulmonary vasodilators including phosphodiesterase inhibitor or nitric oxide * High-grade renal failure \[eGFR\<45\] mL/min/1.73 m2 - serum potassium \>5.3 mmol/L * Multiple organ failure * Non-cardiac condition that limits life span for \<1 year * Uncontrolled diabetes (HbA1c \>9%) at screening * Active infection (including endocarditis) requiring pharmacotherapy * Sepsis * Active hemorrhagic disease (e.g., gastrointestinal bleeding, injury) * History of cardiac transplantation * Immune system-altering medications, or immunosuppressive therapy at the time of enrolment or within the prior 12 weeks * Dystrophin-associated cardiomyopathy confirmed by standard cardiomyopathy panel testing * Confirmed myocarditis at time of screening * Elevated LFTs greater than 2 times upper limit of normal at time of consent * Elevated WBC greater than upper limit of normal as defined by local lab at time of consent * Presence of HLA antibodies specific for therapeutic study product * History of noncompliance, alcohol abuse, recreational drug use, or incarceration within the last year * Currently pregnant or breastfeeding * Unsafe/unfeasible to enroll due to PI/designee discretion