New drug aims to stop breast cancer recurrence in High-Risk patients
NCT ID NCT04595565
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 3 trial tests whether the drug sacituzumab govitecan (Trodelvy) can prevent breast cancer from returning in patients with HER2-negative breast cancer who still have cancer after initial chemotherapy. About 1,332 participants will receive either the new drug or standard treatments like capecitabine or platinum chemotherapy. The study compares how long patients live without their cancer coming back.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Sacituzumab govitecan (Trodelvy)
- What this could lead to
- If successful, this could offer a more effective treatment option to prevent breast cancer from returning in patients with a high risk of relapse.
- What could go wrong
- This is a large Phase 3 trial, but the drug may not prove better than existing options, and side effects like severe diarrhea or low blood cell counts are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 1,332 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2020
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Written informed consent prior to beginning specific protocol procedures, including expected cooperation of the patients for the treatment and follow-up, must be obtained and documented according to the local regulatory requirements. 2. Age at diagnosis at least 18 years. 3. Willingness and ability to provide archived formalin fixed paraffin embedded tissue (FFPE) block from surgery after neoadjuvant chemotherapy and from core biopsy before start of neoadjuvant chemotherapy, which will be used for centralized prospective confirmation of HR status, HER2 status, Ki-67 and tumor-infiltrating lymphocytes (TILs) and for retrospective exploratory correlation between genes, proteins, and mRNAs relevant to sensitivity/resistance to the investigational agents. For patients with bilateral carcinoma, FFPE blocks from both sides have to be provided for central testing. 4. Histologically confirmed unilateral or bilateral primary invasive carcinoma of the breast, confirmed histologically by core biopsy. The lead tumor has to be defined by the investigator based on the inclusion criteria for the respective subtype and on the risk status. 5. Centrally confirmed HER2-negative (IHC score 0-1 or FISH negative according to ASCO/CAP guideline) and either * HR-positive (≥1% positive stained cells) disease or * HR-negative (\<1% positive stained cells) assessed preferably on tissue from postneoadjuvant residual invasive disease of the breast, or if not possible, of residual nodal invasion. If not evaluable, core of diagnostic biopsy will be used. In case of bilateral breast cancer, HER2-negative status has to be confirmed for both sides. 6. Patients with residual invasive disease after neoadjuvant chemotherapy at high risk of recurrence defined by either: * For HR-negative: any residual invasive disease \> ypT1mi and/or ypN1\>1mm * For HR-positive disease: a CPS+EG score ≥ 3 or CPS+EG score 2 and ypN+ using local ER and grade assessed on core biopsies taken before start of neoadjuvant treatment. 7. Adequate surgical treatment including resection of clinically evident disease and ipsilateral axillary lymph node dissection. SNB before NACT is discouraged. Axillary dissection before NACT is not permitted. Axillary dissection, including Targeted Axillary Dissection (TAD) should be performed according to guidelines. Histologic complete resection (R0) of all invasive and in situ tumors is required. 8. Patients must have received neoadjuvant taxane-based chemotherapy for 16 weeks (anthracyclines are permitted). This period must include 6 weeks of a taxane containing neoadjuvant chemotherapy (exception: for patients with progressive disease that occurred after at least 6 weeks of taxane-containing neoadjuvant chemotherapy, a total treatment period of less than 16 weeks is also eligible). 9. No clinical evidence for locoregional or distant relapse during or after preoperative chemotherapy. Local progression during chemotherapy is not an exclusion criterion if adequate local control could be obtained. 10. In case of local progression during neoadjuvant therapy, distant metastases must be excluded by adequate imaging (CT/MRI recommend) prior to entering the trial. 11. Immune checkpoint inhibitor / immunotherapy during (neo)adjuvant therapy is allowed until the completion of radiotherapy. 12. Patients with known gBRCA1/2 mutation without indication to adjuvant olaparib therapy are allowed to participate in the trial. 13. An interval of less than 16 weeks since the date of final surgery or less than 10 weeks from completing radiotherapy (whichever occurs last) and the date of randomization is required. 14. Radiotherapy should be delivered before the start of study treatment. Radiotherapy to the breast is indicated in all patients with breast conserving surgery and to the chest wall and lymph nodes according to local guidelines as well as in all patients with cT3/4 or ypN+ disease treated by mastectomy. 15. Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1. 16. Resolution of all acute toxic effects of prior anti-cancer therapy or surgical procedure or radiotherapy to NCI CTCAE v 5.0 grade ≤ 1 (except alopecia or other toxicities not considered a safety risk for the patients at the investigator´s discretion). 17. Estimated life expectancy of at least 5 years irrespective of the diagnosis of breast cancer. 18. The patient must be accessible for scheduled visits, treatment and follow-up. 19. Normal cardiac function after neoadjuvant chemotherapy must be confirmed according to local guidelines. Results for LVEF must be above the normal limit of the institution. 20. Laboratory requirements: Hematology * Absolute neutrophil count (ANC) ≥1.5 x 109 / L * Platelets ≥100 x 109 / L * Hemoglobin ≥10 g/dL (≥6.2 mmol/L) Hepatic function * Total bilirubin \<1.25x UNL * AST and ALT ≤1.5x UNL * Alkaline phosphatase ≤2.5x UNL Renal Function * \<1.25x ULN creatinine or creatinine clearance ≥30 ml/min (according to Cockroft-Gault, if creatinine is above UNL). 21. Negative pregnancy test (urine or serum) within 14 days prior to randomization for all women of childbearing potential. A woman is considered to be of childbearing potential if she is not postmenopausal. Postmenopausal is defined as: * Age ≥60 years * Age \<60 years and ≥12 continuous months of amenorrhea with no identified cause other than menopause * Surgical sterilization (bilateral oophorectomy and/or hysterectomy). 22. For women of childbearing potential and males with partners of childbearing potential: agreement to remain abstinent (refrain from heterosexual intercourse) or use contraceptive methods that result in a failure rate of \< 1% per year during the treatment period and for at least 6 months after the last dose of sacituzumab govitecan for female patients and for at least 3 months for male patients; for at least 6 months after the last dose of capecitabine or carboplatin/cisplatin for female patients and for at least 3 months after the last dose of capecitabine or 6 months after the last dose of carboplatin/cisplatin for male patients. Examples of non-hormonal contraceptive methods with a failure rate of \< 1% per year include: bilateral tubal ligation; male partner sterilization; intrauterine devices. 23. Complete staging work-up prior to the initiation of neoadjuvant chemotherapy. Missing staging investigations must be performed prior to randomization. Exclusion Criteria: 1. Known hypersensitivity reaction to one of the compounds or substances used in this protocol. 2. Patients with definitive clinical or radiologic evidence of stage IV cancer (metastatic disease) are not eligible. 3. Patients with known gBRCA1/2 mutation and indicated or planned adjuvant olaparib therapy if available. 4. Patients with a history of any malignancy are ineligible with the following exceptions: * Patient has been disease-free for at least 5 years and is at low risk for recurrence of that malignancy * CIS of the cervix, basal cell and squamous cell carcinomas of the skin. 5. Female patients: pregnancy or lactation at the time of randomization or intention to become pregnant during the study and up to 6 months after sacituzumab govitecan and up to 6 months after treatment with capecitabine or carboplatin/cisplatin. 6. Severe and relevant co-morbidity that would interact with the application of cytotoxic agents or the participation in the study, including Gilbert´s disease, Crigler-Najjar-Syndrome, known hepatitis B, hepatitis C, known HIV positivity or known autoimmune disease other than diabetes, vitiligo, or stable thyroid disease, vitiligo, or other autoimmune skin disease with dermatologic manifestations only are permitted provided all of the following conditions are met: * Rash must cover \< 10% of body surface area * Disease is well controlled at baseline and requires only low-potency topical corticosteroids * No occurrence of acute exacerbations of the underlying condition requiring psoralen plus ultraviolet A radiation (PUVA), methotrexate, retinoids, biologic agents, oral calcineurin inhibitors, or high-potency or oral corticosteroids within the previous 12 months. 7. Any condition that interferes with the safe administration of the treatment of physician´s choice in case the patient is randomized into the TPC arm. 8. Known or suspected congestive heart failure (\>NYHA I) and/or coronary heart disease, angina pectoris requiring antianginal medication, previous history of myocardial infarction, evidence of prior infarction on ECG, uncontrolled or poorly controlled arterial hypertension (i.e. BP \>150/90 mmHg under treatment with at maximum three antihypertensive drugs), rhythm abnormalities requiring permanent treatment (excluding chronic atrial fibrillation not requiring a pacemaker), clinically significant valvular heart disease, supraventricular and nodal arrhythmias requiring a pacemaker or not controlled with medication;conduction abnormality requiring a pacemaker. 9. History of idiopathic pulmonary fibrosis, organizing pneumonia (e.g. bronchiolitis obliterans), drug-induced pneumonitis, idiopathic pneumonitis or active pneumonitis on chest CT scan. 10. Receipt of live attenuated vaccination within 30 days prior to study entry or within 30 days of receiving chemotherapy. 11. History of significant neurological or psychiatric disorders including psychotic disorders, dementia or seizures that would prohibit the understanding and giving of informed consent. 12. Any condition that, in the opinion of the investigator, would interfere with evaluation of study treatment or interpretation of patient safety or study results. 13. Known allergic reactions to irinotecan. 14. Concurrent treatment with: * Chronic corticosteroids prior to study entry with the exceptions of intranasal and inhaled corticosteroids or systemic corticosteroids at physiological doses, which are not to exceed 10 mg/day of prednisone, or equivalent corticosteroid.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AGAPLESION Markus Krankenhaus
Frankfurt am Main, Hesse, 60431, Germany
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Beaumont Hospital
Dublin, D09V2N0, Ireland
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Breast Center KSSG
Sankt Gallen, 9007, Switzerland
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Brust-Zentrum Zürich
Zurich, 8008, Switzerland
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CH Fleyriat
Bourg-en-Bresse, 1000, France
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CHU Bretonneau
Tours, 37044, France
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CHU UCL Namur/Site Sainte Elisabeth
Namur, 5000, Belgium
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CHU de Limoges
Limoges, 87042, France
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COMPLEJO HOSPITALARIO UNIVERSITARIO A CORUÑA-Hospital Teresa Herrera (CHUAC)
A Coruña, 15009, Spain
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Caritasklinik St. Theresia
Saarbrücken, Saarland, 66113, Germany
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Centre Antoine Lacassagne
Nice, 6189, France
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Centre Eugène Marquis
Rennes, 35042, France
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Centre François Baclesse
Caen, 14000, France
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Centre Georges François Leclerc
Dijon, 21000, France
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Centre Henri Becquerel
Rouen, 76000, France
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Centre Hospitalier de Pau
Pau, 64000, France
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Centre Jean Perrin 5
Clermont-Ferrand, 63011, France
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Centre Leon Berard
Lyon, 69373, France
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Centre Oscar Lambret
Lille, 59020, France
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Centrum für Hämatologie und Onkologie am Bethanien-Krankenhaus
Frankfurt am Main, Hesse, 60389, Germany
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Charité Campus Mitte, BIH Charité Rahel Hirsch
Berlin, Brandenburg, 10117, Germany
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Clinica Universidad de Navarra
Madrid, 28027, Spain
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Clinica Universidad de Navarra
Pamplona, 31008, Spain
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Clinique Tivoli Ducos
Bordeaux, 33000, France
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Complejo Hospitalario Universitario de Albacete
Albacete, 2006, Spain
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Complejo Hospitalario Universitario de Santiago (Chus)
Santiago de Compostela, 15706, Spain
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Complejo Hospitalario de Jaén
Jaén, 23007, Spain
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Consorci Hospital General Universitari de Valencia
Valencia, 46014, Spain
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Consorci Sanitari Del Maresme
Mataró, 08304, Spain
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Consorcio Hospitalario Provincial de Castellón
Castellon, 12002, Spain
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Cork University Hospital
Cork, T12 DFK4, Ireland
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DIAKOVERE Henriettenstift Gynäkologie
Hanover, Lower Saxony, 30559, Germany
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DONAUISAR Klinikum Deggendorf
Deggendorf, 94469, Germany
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Elisabeth Krankenhaus
Kassel, Hesse, 34117, Germany
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Fundación Instituto Valenciano de Oncología
Valencia, 46009, Spain
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Gcs Rissa
Sarcelles, 95200, France
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Gemeinschaftspraxis Dallacker / Eilers
Wolfenbüttel, Lower Saxony, 38304, Germany
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Gemeinschaftspraxis Dres. Heinrich / Bangerter
Augsburg, Bavaria, 86150, Germany
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Gustave Roussy Cancer Campus
Villejuif, 94800, France
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HELIOS Klinikum Berlin Buch
Berlin, 13125, Germany
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Heinrich-Heine-Universität Düsseldorf
Düsseldorf, North Rhine-Westphalia, 40225, Germany
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Helios Klinik Wiesbaden
Wiesbaden, Hesse, 65199, Germany
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Helios Universitätsklinikum Wuppertal
Wuppertal, North Rhine-Westphalia, 42283, Germany
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Hochwaldkrankenhaus, Gesundheitszentrum Wetterau gGmbH
Bad Nauheim, Hesse, 61231, Germany
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Hospital Clinico Universitario Virgen de la Victoria
Málaga, 29010, Spain
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Hospital Clinico Universitario de Valencia
Valencia, 46010, Spain
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Hospital Clínico Universitario Virgen de La Arrixaca
Murcia, 30120, Spain
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Hospital Clínico Universitario de Valladolid
Valladolid, 47003, Spain
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Hospital Galdakao-Usansolo
Galdakao, 48960, Spain
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Hospital General Universitario Morales Meseguer
Murcia, 3008, Spain
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Hospital General Universitario de Alicante
Alicante, 3010, Spain
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Hospital Iniversitario De Toledo
Toledo, 45007, Spain
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Hospital Quirónsalud Sagrado Corazón
Seville, 41013, Spain
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Hospital San Pedro de Alcántara
Cáceres, 10003, Spain
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Hospital Universitari Sant Joan de Reus
Reus, 43204, Spain
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Hospital Universitari Son Espases
Palma de Mallorca, 07120, Spain
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Hospital Universitari Son Llátzer
Palma de Mallorca, '07198, Spain
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Hospital Universitario 12 de Octubre
Madrid, 28041, Spain
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Hospital Universitario Araba-Txagorritxu
Vitoria-Gasteiz, 01009, Spain
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Hospital Universitario Clinico San Cecilio
Granada, 18016, Spain
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Hospital Universitario Fundación Alcorcón
Alcorcón, 28922, Spain
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Hospital Universitario La Paz
Madrid, 28046, Spain
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Hospital Universitario Ntra.Sra. de Candelaria
Santa Cruz de Tenerife, 38010, Spain
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Hospital Universitario Quirónsalud Madrid
Pozuelo de Alarcón, 28223, Spain
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Hospital Universitario Ramón Y Cajal
Madrid, 28034, Spain
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Hospital Universitario San Carlos
Madrid, 28040, Spain
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Hospital Universitario Severo Ochoa
Leganés, 28911, Spain
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Hospital Universitario Virgen de La Macarena
Seville, 41009, Spain
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Hospital Universitario de Canarias
San Cristóbal de La Laguna, 38320, Spain
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Hospital Universitario de Cruces
Barakaldo, Bizkaia, 48903, Spain
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Hospital Universitario de Fuenlabrada
Fuenlabrada, 28942, Spain
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Hospital Universitario de Salamanca
Salamanca, 37007, Spain
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Hospital Virgen de Los Lirios
Alcoy, 03804, Spain
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Hospital de La Santa Creu I Sant Pau
Barcelona, 08041, Spain
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Hämato-Onkologie im Medicum
Bremen, Free Hanseatic City of Bremen, 28209, Germany
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Hämatologie-Onkologie im Zentrum MVZ GmbH
Augsburg, 86150, Germany
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Hôpital Privé Des Côtes d'Armor- Centre CARIO-HPCA
Plérin, 22190, France
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Hôpital privé du Confluent
Nantes, 44277, France
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Institut Bergonié
Bordeaux, 33000, France
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Institut Catala D'oncologia
Badalona, 08916, Spain
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Institut Claudius Regaud IUCTO
Toulouse, 31059, France
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Institut Curie (Paris)
Paris, 75005, France
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Institut Godinot
Reims, 51100, France
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Institut Paoli-Calmettes
Marseille, 13009, France
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Institut Sainte Catherine
Avignon, 84918, France
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Institut de Cancérologie Strasbourg Europe-ICANS
Strasbourg, 67200, France
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Institut de cancérologie de l'ouest (Angers)
Angers, 49055, France
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Institut régional du Cancer de Montpellier - ICM Val d'Aurelle
Montpellier, 34298, France
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Johanniter Krankenhaus Genthin-Stendal
Stendal, Saxony-Anhalt, 39576, Germany
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Kantonsspital Graubünden
Chur, 7000, Switzerland
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Kliniken Essen-Mitte Evang. Huyssens-Stiftung/Knappschaft GmbH
Essen, North Rhine-Westphalia, 45136, Germany
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Kliniken der Stadt Köln
Cologne, North Rhine-Westphalia, 51067, Germany
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Klinikum Ernst von Bergmann gGmbH
Potsdam, 14467, Germany
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Klinikum Esslingen GmbH
Esslingen am Neckar, Baden-Wurttemberg, 73730, Germany
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Klinikum Kassel GmbH, Gynäkologische Ambulanz
Kassel, Hesse, 34125, Germany
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Klinikum Landshur GmbH
Landshut, Bavaria, 84034, Germany
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Klinikum Obergöltzsch Rodewisch
Rodewisch, Saxony, 08228, Germany
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Klinikum Oldenburg AöR
Oldenburg, Lower Saxony, 26133, Germany
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Klinikum Passau
Passau, 94032, Germany
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Klinikum Stadt Hanau
Hanau, Hesse, 63450, Germany
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Klinikum Südstadt
Rostock, Mecklenburg-Vorpommern, 18059, Germany
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Klinikum Wels-Grieskirchen GmbH
Wels, 4600, Austria
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Klinikum Worms
Worms, Rhineland-Palatinate, 67550, Germany
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Klinikum am Steinenberg
Reutlingen, Baden-Wurttemberg, 72764, Germany
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Klinikum der J. W. Goethe Universität
Frankfurt am Main, Hesse, 60590, Germany
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Knappschaft Kliniken Marienhospital Bottrop GmbH, Klinik für Gynäkologie und Geburtshilfe
Bottrop, 46236, Germany
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Kreiskliniken Böblingen gGmbH
Böblingen, Baden-Wurttemberg, 71032, Germany
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Kreiskrankenhaus Torgau
Torgau, Saxony, 04860, Germany
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LKH Salzburg - PMU
Salzburg, 5020, Austria
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Landesklinikum Wr. Neustadt
Wiener Neustadt, 2700, Austria
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MUG - Univ.-Klinik f. Frauenheilkunde u. Geburtshilfe Graz
Graz, 8036, Austria
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MUG - Univ.-Klinik f. Innere Medizin Graz
Graz, 8036, Austria
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MUI - Univ. Klinik f. Frauenheilkunde Innsbruck
Innsbruck, 6020, Austria
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MUW - AKH Wien
Vienna, 1090, Austria
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MUW - Med. Univ.-Klinik AKH Wien
Vienna, 1090, Austria
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MVZ Hämatologie-Onkologie Mayen/Koblenz GmbH
Mayen, Rhineland-Palatinate, 56729, Germany
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MVZ II der Niels Stensen Kliniken
Georgsmarienhütte, Lower Saxony, 49124, Germany
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MVZ InnMed-Filiale Traunstein
Traunstein, Bavaria, 83278, Germany
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MVZ Nordhausen gGmbH im Südharz Krankenhaus
Nordhausen, Thuringia, 99734, Germany
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MVZ für Hämatologie und Onkologie Ravensburg GmbH
Ravensburg, 88212, Germany
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MVZ in der Klinik Dr. Hancken
Stade, Lower Saxony, 21680, Germany
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Mammazentrum Hamburg
Hamburg, Free and Hanseatic City of Hamburg, 20364, Germany
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Marienhospital Bottrop gGmbH
Bottrop, North Rhine-Westphalia, 46236, Germany
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MediOnko-Institut GbR
Berlin, State of Berlin, 10367, Germany
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Oncologianova GmbH
Recklinghausen, North Rhine-Westphalia, 45659, Germany
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Onkologische Schwerpunkt- Praxis Speyer
Speyer, Rhineland-Palatinate, 67346, Germany
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Onkologische Schwerpunktpraxis, Studiengesellschaft Onkologie Bielefeld GbR
Bielefeld, Nordrhein-Wastfalen, 33604, Germany
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Ordensklinikum Linz GmbH - BHS
Linz, 4010, Austria
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Parc Tauli Hospital Universitari
Sabadell, 08208, Spain
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Praxis Dr. B. Adhami
Erkelenz, North Rhine-Westphalia, 41812, Germany
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Praxisklinik für Hämatologie und Onkologie
Koblenz, Rhineland-Palatinate, 56068, Germany
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Rotkreuzklinikum München
München, 80634, Germany
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SRH Wald-Klinikum Gera gGmbH, Brustzentrum Ostthüringen
Gera, Thuringia, 07548, Germany
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SRH Zentralklinikum Suhl
Suhl, Thuringia, 98527, Germany
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Salzkammergut-Klinikum Vöcklabruck
Vöcklabruck, 4840, Austria
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Sana Klinikum Offenbach
Offenbach, Hesse, 63069, Germany
-
Schwarzwald-Baar-Klinikum
Villingen-Schwenningen, Baden-Wurttemberg, 78052, Germany
-
Schwarzwald-Baar-Klinikum
Villingen-Schwenningen, 78052, Germany
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Schwerpunktpraxis der Gynäkologie und Onkologie
Fürstenwalde, Brandenburg, 15517, Germany
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Sozialstiftung Bamberg, Klinik am Bruderwald
Bamberg, Bavaria, 96049, Germany
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St James's Hospital
Dublin, D08 NHY1, Ireland
-
St Vincent's University Hospital
Dublin, D04 T6F4, Ireland
-
St, Johannes Hospital
Dortmund, North Rhine-Westphalia, 44137, Germany
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St. Elisabeth-Krankenhaus, Brustzentrum Köln-Hohenlind
Cologne, North Rhine-Westphalia, 50935, Germany
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Studien GbR Braunschweig
Braunschweig, Lower Saxony, 38100, Germany
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TumorZentrum Kepler Uniklinikum Linz
Linz, 4020, Austria
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Uniklinikum, Klinik für Geburtshilfe und Gynäkologie
Mainz, Rhineland-Palatinate, 55131, Germany
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University Hospital Limerick
Limerick, V94 F858, Ireland
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University Hospital Virgen Del Rocio S.L.
Seville, 41013, Spain
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University Hospital Waterford
Waterford, X91 ER8E, Ireland
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Universitäsklinik Halle/Saale
Halle, Saxony-Anhalt, 06120, Germany
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Universitätsklinik Erlangen
Erlangen, Bavaria, 91054, Germany
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Universitätsklinikum Aachen
Aachen, North Rhine-Westphalia, 52074, Germany
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Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden
Dresden, Saxony, 01307, Germany
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Universitätsklinikum Essen
Essen, North Rhine-Westphalia, 45147, Germany
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Universitätsklinikum Freiburg
Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany
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Universitätsklinikum Mannheim, Frauenklinik
Mannheim, Baden-Wurttemberg, 68167, Germany
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Universitätsklinikum Münster
Münster, North Rhine-Westphalia, 48149, Germany
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Universitätsklinikum St. Pölten
Sankt Pölten, 3100, Austria
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Universitätsklinikum Ulm
Ulm, Baden-Wurttemberg, 89075, Germany
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Universitätsklinikum Würzburg
Würzburg, 97080, Germany
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ViDia Christliche Kliniken Karlsruhe
Karlsruhe, Baden-Wurttemberg, 76135, Germany
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medius Kliniken gGmbH Nürtingen
Nürtingen, Baden-Wurttemberg, 72622, Germany
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