New combo therapy hopes to boost movement and balance after stroke
NCT ID NCT07597746
First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
This study looks at whether adding a non-invasive brain stimulation technique called rTMS to standard physical therapy can help people with chronic stroke-related weakness improve their movement, balance, and quality of life. Twenty adults who had a stroke at least six months ago will receive the combined treatment. The goal is to see if this approach is safe and offers extra benefits beyond therapy alone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of first-ever unilateral ischemic or hemorrhagic stroke confirmed by neuroimaging (CT or MRI) * Chronic post-stroke hemiplegia (≥ 6 months since stroke onset) * Moderate to severe motor impairment of the affected lower limb (FMA-LE score between 10 and 28 points) * Age between 18 and 75 years * Medically stable and able to participate in a rehabilitation program * Ability to understand study procedures and provide written informed consent * No contraindications to repetitive transcranial magnetic stimulation (rTMS), according to current safety guidelines. Exclusion Criteria: * History of epilepsy or seizures * Presence of pacemakers, cochlear implants, intracranial metallic implants, or other contraindications to rTMS * Severe cognitive impairment or communication deficits preventing participation * Progressive neurological disorders or unstable medical conditions * Participation in other experimental neurorehabilitation interventions during the study period * Any condition judged by investigators to compromise safety or data valid
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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Other studies related to the condition(s) this trial covers.
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