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Can brain zaps and hearing aids boost memory in seniors?

NCT ID NCT07389213

Symptom relief Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether combining a non-invasive brain stimulation technique called rTMS with hearing aids can improve cognitive function in older adults with age-related hearing loss. About 189 participants, including those with and without hearing aids, will receive two 14-day courses of rTMS and be tested on memory, thinking, and brain activity. The goal is to see if this combination can help slow or reverse cognitive decline.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive Transcranial Magnetic Stimulation (rTMS) device
What this could lead to
If it works, this could point toward a non-drug way to slow or improve cognitive decline in older adults with hearing loss.
What could go wrong
This is an early real-world study, not a large randomized trial. Results may not apply to everyone, and the cognitive benefits of rTMS are still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 189 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 85 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥50 years and ≤85 years, regardless of gender. 2. Diagnosed with age-related hearing loss (ARHL), characterized by symmetrical, slowly progressing hearing loss primarily affecting high frequencies, along with decreased speech recognition ability due to aging. This is in accordance with the "Expert Consensus on Diagnosis and Intervention of Age-Related Hearing Loss" 2019 edition.(Only ARHL-nonHA group and ARHL-HA group) 3. The better ear has moderate, moderately severe, or severe hearing loss (based on the 2021 WHO hearing classification standards, i.e., PTA between 35～79dB). 4. Wearing hearing aids for more than half a year, with daily wearing time exceeding 7.2 hours; (Only ARHL-HA group) 5. Chinese nationals who can complete all assessments in Chinese. 6. Right-handed. 7. Educational level of at least 6 years. 8. Informed consent obtained, agreeing to participate in the trial with no plans to relocate within one year. Exclusion Criteria: 1. Exclusion of hearing loss due to noise, genetics, ototoxic drugs, or other non-age-related causes; 2. History of central nervous system disorders such as cerebral infarction, stroke, epilepsy, or traumatic brain injury; 3. Diagnosis of dementia or other neurodegenerative diseases that affect compliance with the study; 4. Presence of major neurological disorders, severe systemic diseases, family history of hereditary conditions, or major psychiatric disorders; 5. Contraindications to MRI; 6. Contraindications to rTMS.

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Conditions

The condition(s) this trial relates to.

presbycusis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Senile deadness

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sun Yat-sen Memorial Hospital of Sun Yat-sen University

    RECRUITING

    Guangzhou, Guangdong, 5100000, China

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