Brain wave test may predict depression treatment success
NCT ID NCT05424224
First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
This study tests whether brain wave (EEG) measurements can predict who will get better from a non-invasive magnetic stimulation treatment for depression called rTMS. Researchers will treat 30 adults with depression using rTMS and compare their EEG patterns before and after treatment. The goal is to find brain signal markers that identify responders versus non-responders, which could help personalize depression care in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- repetitive transcranial magnetic stimulation (rTMS) device
- What this could lead to
- If successful, this could help doctors predict which depression patients will respond to rTMS, making treatment more personalized and effective.
- What could go wrong
- This is a small, early-stage study focused on finding brain markers, not on proving rTMS works. The results may not apply to all depression patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2023
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Any adult with symptoms of depression.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Clinical diagnosis of Depression * must be willing to cooperate. Exclusion Criteria: * implanted electronic devices (e.g., pacemaker, medication pump, brain or vagus nerve stimulator, cochlear implant) * history of seizures * intracranial metal (e.g., aneurysm clip) * inability of the participant to cooperate with the Transcranial Magnetic Stimulation (TMS) session
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Florida International University
Miami, Florida, 33174, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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