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New brain zapping technique could silence hallucinations in just two days

NCT ID NCT01022489

Symptom relief Sponsor: University Hospital, Caen Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether high-frequency magnetic stimulation (rTMS) can reduce auditory hallucinations in people with schizophrenia. Unlike standard low-frequency treatment that takes 15 days, this approach uses 20 Hz stimulation over just 2 days, guided by brain scans for precision. 72 participants will receive either real or sham treatment to see if it safely and effectively lessens the voices they hear.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS) device
What this could lead to
If it works, this could offer a faster, more targeted way to reduce auditory hallucinations in people with schizophrenia, potentially shortening treatment from weeks to days.
What could go wrong
This is a mid-stage trial with only 72 participants, so results may not apply to everyone. The treatment is still experimental, and there is a small risk of seizure or headache.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2/3

Runs two stages together: whether the treatment works, then large-scale confirmation.

Participants

72 people

The number who actually took part.

Start date

Aug 2009

Finished

Mar 2015

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with schizophrenic disorders aged from 16 to 65 years old * Patients suffering from auditory hallucinations (score AHRS \> 10) undergoing antipsychotic treatments * patients clinically stabilised (no antipsychotic treatments modifications for the last 2 months * Written signed consent Exclusion Criteria: * Pregnancy or breastfeeding * patients with a brain tumor * Patients with previous history of epilepsy * Patients already treated once by rTMS * Counter-indication to MRI or to rTMS

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Conditions

The condition(s) this trial relates to.

Hallucinations schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Auditory hallucinations in patients with schizophrenic disorders

Contacts and locations

Locations

  • Caen University Hospital

    Caen, 14033, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.