Gene therapy eye injection fails to improve vision in advanced retinitis pigmentosa trial
NCT ID NCT02556736
First seen Jan 12, 2026 · Last updated May 24, 2026 · Updated 20 times
Summary
This early-stage study tested a single injection of RST-001 into the eye for people with advanced retinitis pigmentosa, a genetic condition causing severe vision loss. All 14 participants had very poor vision (hand motion or worse). The main goal was to check safety, and the treatment did not improve vision. The study was completed, but because it did not show benefit, it did not move forward to include people with better eyesight.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cincinnati Eye Institute- Edgewood /ID# 236713
Edgewood, Kentucky, 41017-3415, United States
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Duke Eye Center /ID# 235715
Durham, North Carolina, 27705, United States
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Retina Foundation of the Southwest /ID# 235199
Dallas, Texas, 75231, United States
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University of California San Francisco - Mission Bay /ID# 235717
San Francisco, California, 94158, United States
Conditions
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