New eczema ointment shows promise in early trial
NCT ID NCT07158151
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested an ointment called RSS0393 in 168 adults with mild to moderate atopic dermatitis (eczema). Participants used different strengths of the ointment or a placebo for a set period. The goal was to see if the ointment could clear or nearly clear the skin rash. Results will help decide if larger studies are needed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- RSS0393 ointment
- What this could lead to
- If successful, this could provide a new topical treatment option for adults with mild to moderate atopic dermatitis.
- What could go wrong
- This is a Phase 2 trial with only 168 participants, so results may not confirm effectiveness or safety. The ointment may not work better than placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
168 people
The number who actually took part.
- Started
-
Sep 2025
- Finished
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Apr 2026
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 75 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age ≥18 years old and ≤75 years old at screening. 2. History of atopic dermatitis ≥ 6 months. 3. BSA is between 3% and 20% (inclusive) and EASI score is ≥ 5 and vIGA-AD is 2 or 3. 4. The subjects signed informed consent before any study-related procedures began. Exclusion Criteria: 1. Diagnosis of other dermatologic diseases at screening. 2. Subjects have other skin diseases or conditions that may affect the evaluation of the relevant endpoints of this study. 3. Subjects with any other persistent active autoimmune disease. 4. Subjects who have received topical medication for psoriasis within 14 days before baseline, or systemic medication or phototherapy for psoriasis within 28 days before baseline, or biological agents for psoriasis within a specified time before baseline.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dermatology Hospital of Southern Medical University
Guangzhou, Guangdong, 510091, China