Root canal study: does preparation size determine tooth survival?
NCT ID NCT07583004
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the size of root canal preparation and the amount of remaining tooth structure affect the survival of treated lower molars. Sixty patients with infected pulp will receive either a conventional or conservative root canal preparation. Researchers will track healing and restoration success over time to see which approach works best.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help dentists choose the best root canal preparation size to improve tooth survival and restoration success.
- What could go wrong
- This is a small, early-stage study with only 60 participants, so results may not apply to everyone. It focuses on observation, not a new treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients with mandibular molar teeth diagnosed with symptomatic irreversible pulpitis according to the pulp disease classification recommended by the American Association of Endodontists Patients with active caries in the relevant tooth that would create O, MO/OD, or MOD type cavitations. Patients with periodontally healthy teeth (Grade I mobility or \<4 mm pocket depth). Patients with no systemic diseases (ASA I or II). Patients between the ages of 18-60. Teeth where rubber dam isolation could be achieved. Cases where the remaining sound tooth structure allowed for a direct composite restoration. Exclusion Criteria:Teeth with non-vital pulp and/or observable periapical lesions. Teeth that were not periodontally healthy (Grade II/III mobility or \>3 mm pocket depth). Teeth with complex root canal anatomy (curved canals, C-shaped canals, calcified/obstructed canals, etc.). Patients with systemic diseases, or those who were pregnant or breastfeeding. Patients with parafunctional habits such as bruxism. Teeth without an opposing tooth in the maxillary arch. Teeth that could not be restored due to advanced crown destruction or those with existing prosthetic restorations. Patients whose endodontic treatment had already been initiated elsewhere. Patients who experienced complications during the treatment procedure. \-
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Unişversity of Health Sciences
Ankara, 06120, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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