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Root canal study: does preparation size determine tooth survival?

NCT ID NCT07583004

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how the size of root canal preparation and the amount of remaining tooth structure affect the survival of treated lower molars. Sixty patients with infected pulp will receive either a conventional or conservative root canal preparation. Researchers will track healing and restoration success over time to see which approach works best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help dentists choose the best root canal preparation size to improve tooth survival and restoration success.
What could go wrong
This is a small, early-stage study with only 60 participants, so results may not apply to everyone. It focuses on observation, not a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2024

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients with mandibular molar teeth diagnosed with symptomatic irreversible pulpitis according to the pulp disease classification recommended by the American Association of Endodontists Patients with active caries in the relevant tooth that would create O, MO/OD, or MOD type cavitations. Patients with periodontally healthy teeth (Grade I mobility or \<4 mm pocket depth). Patients with no systemic diseases (ASA I or II). Patients between the ages of 18-60. Teeth where rubber dam isolation could be achieved. Cases where the remaining sound tooth structure allowed for a direct composite restoration. Exclusion Criteria:Teeth with non-vital pulp and/or observable periapical lesions. Teeth that were not periodontally healthy (Grade II/III mobility or \>3 mm pocket depth). Teeth with complex root canal anatomy (curved canals, C-shaped canals, calcified/obstructed canals, etc.). Patients with systemic diseases, or those who were pregnant or breastfeeding. Patients with parafunctional habits such as bruxism. Teeth without an opposing tooth in the maxillary arch. Teeth that could not be restored due to advanced crown destruction or those with existing prosthetic restorations. Patients whose endodontic treatment had already been initiated elsewhere. Patients who experienced complications during the treatment procedure. \-

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Unişversity of Health Sciences

    Ankara, 06120, Turkey (Türkiye)

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