Which root canal filler hurts less? new study aims to find out
NCT ID NCT07410780
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at two types of dental sealers used in root canals to see which one causes less pain afterward. About 50 adults with tooth pain will get one of the two sealers and report their pain for three days. The goal is to help dentists choose the sealer that makes root canals more comfortable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-40 years * Single-rooted permanent teeth * Teeth diagnosed with symptomatic irreversible pulpitis * Normal periapical condition on radiographic examination or periodontal ligament (PDL) space widening * Restorable teeth Exclusion Criteria: * Patients with systemic conditions that could alter the course of treatment * Teeth with immature root development * Teeth with necrotic pulp * Teeth exhibiting root resorption * Teeth with calcified root canals
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Operative Dentistry, HITEC-IMS Dental College
RECRUITINGRawalpindi, Punjab Province, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Steroid rinse inside the tooth: a new way to curb root canal pain?
- Which root canal file leaves less pain? trial puts two systems to the test
- Chilling the root: could cryotherapy cool Post-Dental pain?
- Can a gentler root canal tool ease post-treatment pain?
- Could a simple injection make root canals less painful?
- Could a simple steroid shot make root canals less painful?