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Which root canal method hurts less? study finds answer in one week

NCT ID NCT07355816

Symptom relief Sponsor: Cumhuriyet University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at different ways to clean a tooth during a root canal to see which one causes the least pain afterward. 80 healthy adults with a dead tooth in the lower jaw received one of several disinfection methods. Their pain was checked at 6, 24, 48, and 72 hours, and again on day 7. The goal was to find the gentlest cleaning method for a more comfortable recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Jun 2023

Finished

Nov 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria * Systemically healthy individuals between the ages of 18 and 65, * Adequate mouth opening, * Asymptomatic devitaled mandibular premolar with a single root and single canal, * Negative response to cold and electric pulp tests and no bleeding at the pulp chamber opening, * Able to provide rubber dam isolation, * Presence of opposing teeth. Exclusion criteria * Presence of mental or psychiatric disorders, * Allergic diseases, * Use of painkillers within 12 hours or antibiotics within 1 week before the procedure, * Swelling, palpation/percussion pain, or sinus tract before treatment, * Presence of a periodontal pocket greater than 3 mm in diameter on the involved tooth, * Presence of a periapical radiolucency greater than 5 mm in diameter associated with the involved tooth, * Initiation of root canal treatment, * Irreparable material loss, root fracture, or crack, * Severe mobility, * Open apex, * Severe root canal calcification, * Internal or external resorption, * Bruxism, * Complaints of pain elsewhere in the mouth or in a tooth, * Being pregnant or breastfeeding.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain, postoperative

Contacts and locations

Locations

  • Faculty of Dentistry, Cumhuriyet University, Sivas

    Sivas, 58000, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.