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Osteoporosis drug safety checked in indian women

NCT ID NCT06079476

First seen Nov 03, 2025 · Last updated Jun 23, 2026 · Updated 29 times

Summary

This study tested the safety and tolerability of romosozumab (Evenity) in 100 postmenopausal women in India who have osteoporosis and a high risk of bone fractures. Researchers monitored side effects, serious adverse events, and changes in lab tests and vital signs. They also measured bone density improvements in the spine and hip.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Apollo Hospital

    New Delhi, National Capital Territory of Delhi, 110076, India

  • Christain Medical College

    Vellore, Tamil Nadu, 632004, India

  • King Edward Memorial Hospital And Seth Gordhandas Sunderdas Medical College

    Mumbai, Maharashtra, 400012, India

  • King Georges Medical University

    Lucknow, Uttar Pradesh, 226 003, India

  • MGM Healthcare

    Chennai, Tamil Nadu, 600 029, India

  • MS Ramaiah Medical College and Hospitals

    Bangalore, Karnataka, 560054, India

  • Post Graduate Institute of Medical Education and Research

    Chandigarh, Punjab, 160 012, India

  • Sancheti Institute for Orthopedics and rehabilitation

    Pune, Maharashtra, 411005, India

  • Sir Ganga Ram Hospital

    New Delhi, National Capital Territory of Delhi, 110060, India

  • Stavya Spine Hospital and Research Institute SSHRI

    Ahmedabad, Gujarat, 380 007, India

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

romosozumab (Evenity)

What this could lead to

If successful, this study could confirm that romosozumab is a safe and tolerable option for Indian women with osteoporosis, helping reduce fracture risk.

What could go wrong

This is a small, single-arm, completed Phase 4 study with no placebo group, so results may not be generalizable. Safety findings are limited to 100 participants.

Conditions

The condition(s) this trial relates to.

osteoporosis postmenopausal osteoporosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.