Scientists probe body's own fat-making signals for obesity clues
NCT ID NCT07567287
First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
This study looks at how certain natural chemicals (endocannabinoids) influence the development of fat cells from stem cells found in belly fat. Researchers will take small fat samples from 30 people undergoing abdominal surgery, including healthy controls, people with obesity, and those with both obesity and type 2 diabetes. The goal is to understand these processes better, which could lead to new treatments for obesity and diabetes in the future.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2026
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Control group : * Men or postmenopausal women aged 18 to 80 * Individuals who have provided their free and informed written consent * Individuals scheduled to undergo abdominal surgery * Non-diabetic obese individuals : * Men or postmenopausal women aged 18 to 80 * BMI \> 30 - Individuals who have provided written, free, and informed consent * Scheduled to undergo abdominal surgery * Obese individuals with diabetes : * Men or postmenopausal women aged 18 to 80 with type 2 diabetes not treated with insulin or a GLP-1 agonist * BMI \> 30 * Individuals who have provided written, free, and informed consent and are scheduled to undergo abdominal surgery Exclusion Criteria : * Control group : * Individuals not enrolled in or eligible for a social security program * Individuals subject to legal guardianship (curatorship, guardianship) * Individuals subject to judicial protective measures * Pregnant women, women in labor, or breastfeeding women * Adults who are legally incapacitated or unable to give consent * Minors * BMI \> 30 * Diabetes * Chronic inflammatory disease * Cancer undergoing chemotherapy or having undergone chemotherapy within the past year * Gastrointestinal cancer with recent weight loss and/or malnutrition * Known metastatic cancers * Cancers undergoing long-term hormonal therapy * Any positive result for screening for human immunodeficiency virus (HIV) infection, hepatitis B surface antigen testing, or testing for antibodies against the hepatitis C virus (HCV) with a positive HCV RNA test. * Non-diabetic obese individuals : * Individuals not enrolled in or eligible for a social security program * Individuals subject to legal guardianship (curatorship, guardianship) * Individuals subject to judicial protective measures * Pregnant women, women in labor, or breastfeeding women * Adults who are legally incapacitated or unable to give consent * Minors * Diabetes * Chronic inflammatory disease * Cancer undergoing chemotherapy or having undergone chemotherapy within the past year * Gastrointestinal cancer with recent weight loss and/or malnutrition * Known metastatic cancers * Cancers undergoing long-term hormonal therapy, * Any positive result for screening for human immunodeficiency virus (HIV) infection, hepatitis B surface antigen, or antibodies to hepatitis C virus (HCV) with a positive HCV RNA test. * Obese individuals with diabetes * Individuals not enrolled in or not eligible for a social security program * Individuals subject to legal guardianship (curatorship, guardianship) * Individuals subject to judicial protective measures * Pregnant women, women in labor, or breastfeeding women * Adults who are legally incapacitated or unable to give consent * Minors * Diabetes * Chronic inflammatory disease * Cancer undergoing chemotherapy or having undergone chemotherapy within the past year * Gastrointestinal cancer with recent weight loss and/or malnutrition * Known metastatic cancers * Cancers undergoing long-term hormonal therapy, * Any positive result for screening for human immunodeficiency virus (HIV) infection, hepatitis B surface antigen, or antibodies against hepatitis C virus (HCV) with a positive HCV RNA test.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Chu Dijon Bourgogne
RECRUITINGDijon, France
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