Robotic surgery for thyroid cancer: a Scar-Free alternative?
NCT ID NCT06623578
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two surgical approaches for papillary thyroid cancer that has spread to lymph nodes in the neck: robotic surgery through the armpit versus traditional open surgery. The goal is to see if the robotic method offers similar cancer control and survival rates while improving quality of life and reducing visible scarring. About 876 participants will be followed for five years to measure disease-free survival and overall well-being.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- robotic-assisted surgery
- What this could lead to
- If successful, this could show that robotic surgery is as effective as open surgery for removing thyroid cancer and lymph nodes, with better cosmetic results and quality of life.
- What could go wrong
- This is a large trial but still early in terms of long-term outcomes. Robotic surgery may not be suitable for all patients, and there could be risks like nerve injury or incomplete cancer removal.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 876 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2024
- Expected to finish
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Dec 2033
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-70 years old, male or female; * papillary thyroid carcinoma with ipsilateral lateral cervical lymph node metastasis confirmed by FNAB; * thyroid tumor of less than 3.0 cm in the largest diameter; * lack of extrathyroidal extensions as estimated by preoperative ultrasonography and CT. Exclusion Criteria: * level I or contralateral neck node metastases. * enlarged lymph node of larger than 2.0 cm in the short diameter. * suspected perinodal infiltration of metastatic lymph nodes. * cervical or/and thoracic deformity. * life-threatening diseases of liver, kidney, heart and other organs, or abnormal coagulation function. * clinical evidence of distant metastases such as in the lung, bone, and so on. * history of previous neck surgery and/or radiation therapy. * intolerable to general anesthesia * refuse either surgical procedure * unwilling to cooperate with long-term follow-up evaluation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sun Yat-sen Memorial Hospital
RECRUITINGGuangzhou, Guangdong, 510120, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Mapping how thyroid tumors spread and what surgery leaves behind
- Freezing out thyroid tumors: a new weapon in the fight?
- AR goggles could help surgeons spot cancer cells left behind during breast cancer surgery
- Scientists mine 1,100 patient records to spot thyroid cancer return risks
- Robotic surgery through the mouth could eliminate neck scars in thyroid cancer patients
- AI assistant aims to ease thyroid cancer anxiety before surgery