Triple therapy targets aggressive blood cancer in early trial
NCT ID NCT05672173
First seen Dec 17, 2025 · Last updated May 23, 2026 · Updated 19 times
Summary
This study tests a combination of three treatments for Richter's transformation, an aggressive form of blood cancer. The approach uses the patient's own immune cells (liso-cel) plus two drugs (nivolumab and ibrutinib) to boost the immune system and block cancer growth. About 20 adults whose cancer has returned or not responded to prior therapy will participate. The goal is to see if this combination can shrink tumors and how safe it is.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Conditions
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