Could a simple blood flow trick help kids with CP walk better?
NCT ID NCT07390760
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether remote ischemic conditioning (RIC) — brief cycles of cutting off and restoring blood flow to a limb — combined with balance training can improve balance and spinal reflexes in children with cerebral palsy (CP). Sixteen children aged 8-17 with mild to moderate CP will receive either real RIC or a sham version alongside balance exercises. The goal is to see if RIC boosts the training's effects on movement and spasticity.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Remote ischemic conditioning (brief cycles of blood flow restriction and release) plus balance training
- What this could lead to
- If it works, this could point toward a simple, non-drug way to improve balance and reduce spasticity in children with cerebral palsy.
- What could go wrong
- This is a very small early study (16 children) with no placebo control for the training. Results may not apply to all children with CP, and the benefits may be small or temporary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 16 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Jul 2025
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
8 to 17 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children diagnosed with cerebral palsy (CP) between the ages 8-17 years * Gross motor function classification system levels I-III * Mainstream in school and has sufficient cognition to follow the experiment instructions Exclusion Criteria: * Children with other developmental disabilities such as autism and developmental coordination disorders * Children with cognitive deficits such as inability to understand and follow commands, substantially lower performance at grade level in school, and/or communication problems * Children with balance disorders such as vestibular disorders, posterior fossa tumor etc. * Children with known cardiorespiratory dysfunctions * Children with sickle cell disease * Children who are receiving other adjunct therapies such as transcranial magnetic stimulation, transcranial direct current stimulation, or vagal nerve stimulation * Presence of lower extremity condition, injury, or surgery within last three months which could compromise conditioning and training. * Participants who are pregnant.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Children with cerebral palsy are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
East Carolina University
RECRUITINGGreenville, North Carolina, 27834, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.