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Pain relief showdown for broken ribs: IV lidocaine vs nerve block

NCT ID NCT04707183

Symptom relief Sponsor: Stanford University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to compare two ways to manage pain from broken ribs: a continuous IV drip of lidocaine versus a nerve block called an erector spinae plane (ESP) block. The goal was to see which method reduces pain and improves breathing better. However, the study was withdrawn before any patients were enrolled, so no results were obtained.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
lidocaine
What this could lead to
If successful, this could show that an ESP nerve block provides better pain relief for rib fractures than IV lidocaine, potentially improving recovery.
What could go wrong
The study was withdrawn before starting, so no results are available. Even if conducted, it was a small Phase 2 trial, so findings would be preliminary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Expected to start

May 2025

An estimate. Start dates often move.

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- All adult patients admitted to Stanford Health Care with two or more acute traumatic rib fractures. Exclusion Criteria: * Hemodynamically instability, * Mechanical ventilation, * Polytrauma (defined as bone or organ injury outside the thorax), * Pregnancy, * Incarceration * Local anesthetic allergy or contraindications to lidocaine (Stokes-Adams syndrome, Wolff-Parkinson-White syndrome, or severe degrees of sinoatrial, atrioventricular, or intraventricular block) * Chronic opioid use.

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Conditions

The condition(s) this trial relates to.

bone fracture Rib Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rib fractures

Contacts and locations

Locations

  • Stanford Health Care

    Stanford, California, 94305, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.