Can a light device replace steroid sprays for hay fever?
NCT ID NCT05919316
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a home-use light device (rhinophototherapy) can reduce nasal inflammation and allergy symptoms as well as a standard steroid spray. Thirty-five adults with allergic rhinitis used either the light device for 4.5 minutes three times daily or a steroid spray once daily for two weeks. Researchers measured symptom scores, nasal airflow, and looked at tissue samples for inflammation and damage.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- rhinophototherapy (light device) and mometasone furoate nasal spray (steroid)
- What this could lead to
- If it works, this could offer a drug-free option for managing allergic rhinitis symptoms at home.
- What could go wrong
- This is a small, completed trial with only 35 participants, so results may not apply to everyone. The device requires daily use and may not be more effective than standard sprays.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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35 people
The number who actually took part.
- Started
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Jul 2023
- Finished
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Nov 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients 18 years and above * Newly diagnosed allergic rhinitis * Allergic rhinitis is confirmed via positive skin prick test or serum Immunoglobulin E Exclusion Criteria: * Anaphylaxis /poorly controlled bronchial asthma * Refused nasal biopsy * Usage of intranasal corticosteroids and/or antihistamine sprays for the past 1 month * Consumption of oral leukotriene receptor antagonist or oral steroids for the past 1 month * Concomitant nasal pathology (malignancy, chronic rhinosinusitis with nasal polyposis, severe deviated nasal septum) * Bleeding disorder or on anticoagulant/antiplatelet therapy * Recent URTI/Covid-19 within past 14 days * Pregnancy
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Otorhinolaryngology Department, Head and Neck Surgery, Faculty of Medicine, UKM Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, Cheras
Kuala Lumpur, Cheras, 56000, Malaysia
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