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Promising leukemia combo trial pulled before it began

NCT ID NCT07052994

First seen Mar 08, 2026 · Last updated Jun 20, 2026 · Updated 16 times

Summary

This study aimed to find a safe dose of revumenib when given with standard chemotherapy drugs for children and young adults with acute leukemia. It was designed for patients with certain genetic markers. However, the trial was withdrawn before any participants were enrolled, so no data was collected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

revumenib (a targeted drug) combined with chemotherapy drugs (cytarabine, daunorubicin, gemtuzumab ozogamicin)

What this could lead to

If it had worked, this could have pointed toward a new treatment option for children with certain types of acute leukemia.

What could go wrong

This trial was withdrawn before enrolling any participants, so no results are available. The combination may have caused severe side effects or failed to control the disease.

Conditions

The condition(s) this trial relates to.

childhood leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.