Which nerve block wins for gallbladder surgery pain?
NCT ID NCT07598162
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two types of nerve blocks—retrolaminar block and erector spinae plane block—for pain control after laparoscopic gallbladder removal. One hundred adults aged 20 to 60 will receive one of the two blocks during surgery. The main goal is to see which block delays the need for extra pain medicine and reduces overall opioid use.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- nerve block (local anesthetic injection)
- What this could lead to
- If one block works better, it could mean less pain and less need for strong painkillers after gallbladder surgery.
- What could go wrong
- This is a small, early-stage trial with only 100 people. The results may not apply to everyone, and both blocks might work equally well or have side effects like infection or bleeding.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Age from 20 to 60 years. * Both sexes. * American Society of Anesthesiology (ASA) grade I and II physical status. * Patients will undergo cholecystectomy under general anesthesia. Exclusion Criteria: * • Sensitivities or contraindications to the study medications. * Infection at the site of injection. * Emergency surgery. * Body mass index (BMI) \> 35. * Organic comorbidities. * Histories of psychological conditions and/or chronic pain syndromes. * Contraindications to regional anesthesia. * Severe respiratory, cardiac, hepatic and renal disorders. * Pregnancy. * Coagulopathy. * Opioid addiction.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Sohag Faculty of Medicine
Sohag, Egypt