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Tiny blood vessels may hold key to stronger muscles in old age

NCT ID NCT07680036

Knowledge-focused Sponsor: University of Padova Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This study investigates how tiny blood vessels in muscles influence the ability of older adults to build strength and muscle through resistance training. Researchers will measure muscle size, blood vessel density, and physical function before and after a supervised exercise program. The goal is to understand why some older people respond better to exercise than others, which could lead to more personalized fitness recommendations.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
resistance exercise training
What this could lead to
If successful, this could help design better exercise programs for older adults to maintain muscle mass and function.
What could go wrong
This is a small, early-stage study focused on understanding biological mechanisms, not testing a treatment. Results may not apply to all older adults.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Jan 2024

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 65 years * Body Mass Index (BMI) \>18 and \<30 kg/m² * Stable body weight for at least 3 months prior to enrollment Exclusion Criteria: * Prediabetes or diabetes according to ADA criteria * Chronic diseases, including cardiovascular, liver, respiratory diseases, or cancer * Acute inflammatory conditions, infections, or other clinically significant illnesses * Regular participation in vigorous physical activity (≥2 sessions per week) * Current or recent (within the previous 3 months) treatment with steroid medications * Regular use of protein supplements

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Older adults (65 years and older)

Contacts and locations

Locations

  • Nutrition and Exercise Lab, DSB

    Padova, PD, 35131, Italy

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