Exercise study reveals best way for postmenopausal women to protect their hearts
NCT ID NCT05544357
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how two different ways of doing resistance exercise (short vs long sets) affect the heart and blood vessels of postmenopausal women, both with and without high blood pressure. Sixty women participated, and researchers measured things like blood pressure, heart rate variability, and artery stiffness. The goal was to find which exercise setup is safer and more beneficial for this group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- resistance training (short vs long set configuration)
- What this could lead to
- If successful, this could help design safer, more effective exercise programs for postmenopausal women, especially those with high blood pressure.
- What could go wrong
- This is a small, completed study (60 participants) focused on measuring body responses, not on treating or curing a disease. Results may not apply to all women.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Feb 2023
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * One year since menopause * Physically active (150-300 minutes a week of moderate physical activity or at least 75 minutes a week of vigorous physical activity) * No more than 3 cardiovascular risk factors * Asymptomatic and without cardiovascular (except hypertension), metabolic or renal disease * Hypertensive women should be diagnosed with grade 1 hypertension that must be well controlled by one drug and with low or moderate cardiovascular risk. Exclusion Criteria: * Having grade 2 or 3 hypertension * Participants with hypertension and taking more than one drug for controlling hypertension or by a drug that can interfere cardiovascular responses to exercise * To be or have been receiving hormonal replacement therapy * To show hypertensive response to exercise
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Sport Sciences and Physical Education
Bastiagueiro, A Coruña, 15179, Spain
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